Secondary gout from myelofibrosis
Name the arthritis?
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- There is diffuse soft tissue swelling.
- There is no decreased mineralization of the juxta articular and periarticular carpal and metacarpal bones.
- There are punched out erosive changes involving the base of the right first metacarpal with overhanging sclerotic edges.
- No joint narrowing.
- These findings are extremely concerning for gouty arthritis.
2 case questions available
74-year-old AAF with past medical history significant for
5years ago (JAK2V17F positive)
taking Ruxolitinib 20mg BID , severe pulmonary hypertension,
anemia, history of TIA who presented with complaints of right hand
swelling, warmth and pain after receiving blood transfusion.
She was seen in the hematology clinic and was sent for
a 2 unit blood transfusion. The patient states that since
this blood transfusion she has had pain, swelling, redness and warmth
at the site on her right hand. Interestingly, the patient was
documented by nursing to have received the transfusion in the left hand.
Uric acid was checked and was more than twice normal at 12.8 mg/dl.
She was discharged home on colchicine 0.6 mg bid.
- 1. Jacobson JA, Girish G, Jiang Y et-al. Radiographic evaluation of arthritis: degenerative joint disease and variations. Radiology. 2008;248 (3): 737-47. Radiology (full text) - doi:10.1148/radiol.2483062112 - Pubmed citation
- 2. Nagai Y, Ikebe K, Ito K et-al. A case of secondary gout associated with myelofibrosis following polycythemia vera (author's transl). Rinsho Ketsueki. 1978;19 (3): 226-33. Pubmed citation