Presentation
Two year-old child, with a history of an abnormal post-natal cranial ultrasound scan.
Patient Data
Age: 2
Gender: Female
From the case:
Semilobar holoprosencephaly
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- monoventricle with partially developed occipital and temporal horns, but no frontal horns
- incomplete falx cerebri
- incompletely formed interhemispheric fissure, especially anteriorly
- highly dysplastic corpus callosum
Case Discussion
Semilobar holoprosencephaly is a subtype of holoprosencephaly. It is due to a failure of the midline structures to divide early in the first trimester of pregnancy.