Seminoma (pathology)

Case contributed by Andrew Ryan


Presented with a right testis mass. He had normal serum markers and there was no other radiological evidence of disease. The right testis was removed at operation.

Patient Data

Age: 25 years
Gender: Male

Right testis


There is a circumscribed, homogenous, pale tumor, confined to the testis. The surrounding parenchyma is pale and unremarkable. The attached cord is also visible.


Low power histology - well defined interface between sheets of tumor cells (left) and adjacent testicular parenchyma with compressed seminiferous tubules (right).

High power histology - coalescing nodules of large tumor cells with large nuclei and abundant cleared cytoplasm. The thin strands of intervening stroma contain reactive lymphocytes (compare nuclear size). 

Case Discussion

The features are of pure seminoma. There were no non-seminomatous elements identified. 

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