Sickle cell anemia

Case contributed by Dr Laughlin Dawes

Presentation

Symptoms of chest infection.

Patient Data

Age: 30
Gender: Female
X-ray

The lateral CXR shows multiple vertebral end-plate irregularities and depressions. The peripheral portions of the end-plates are spared. The appearance is due to bone infarction and subsequent collapse. 

Case Discussion

The patient had a history of sickle-cell anemia.

This is an early example of the classical H-shaped vertebrae seen in sickle-cell anemia. H-shaped vertebrae are a characteristic finding seen in ~10% of patients with the disease. Bone infarction may be complicated by Salmonella osteomyelitis. Other signs to look for on chest films are cardiomegaly, absent spleen, and cholecystectomy clips.

PlayAdd to Share

Case information

rID: 35877
Published: 6th May 2015
Last edited: 6th Jul 2019
Inclusion in quiz mode: Included

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.