Presentation
Back pain with limited movement. The patient is a known case of sickle cell disease.
Patient Data
Irregular-shaped, serpiginous lesions are seen involving multiple lower dorsal, lumbar, and sacral vertebrae, showing an outer sclerotic dark signal line, an internal high signal line, and a core of fatty marrow.
Multilevel central end-plate depression gives rise to the H-shaped vertebrae.
Mottled bone marrow signal intensity with low marrow T1 signal is noted.
Case Discussion
This case demonstrates skeletal manifestations of sickle cell disease, including bone infarcts due to vaso-occlusive crises and H-shaped vertebrae as a result of osteonecrosis.
Mottled bone marrow signal intensity with low T1 signal possibly represents red marrow reconversion due to chronic anaemia or iron deposition.
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