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Sinistral portal hypertension - secondary to pancreatic carcinoma

Case contributed by Melisa Sia
Diagnosis probable

Presentation

Known pancreatic cancer with liver metastasis. For restaging.

Patient Data

Age: 60 years
Gender: Female

47 mm low attenuation mass centered on the pancreatic tail, with infiltration of the left adrenal gland and the celiac axis.
Associated splenic vein occlusion.
There is evidence of segmental portal hypertension with gastric varices. 
No features to suggest background chronic liver disease. 
No splenomegaly. No free fluid.

Case Discussion

Sinistral (or segmental) portal hypertension occurs as a result of splenic vein occlusion, most commonly secondary to pancreatic pathology (pancreatitis, pseudocyst or carcinoma).

The most common features include esophageal or gastric varices, which can bleed acutely. 

Concurrent systemic portal hypertension should be excluded.

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