Sinonasal undifferentiated carcinoma
16 Y/O patient with nasal fullness
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There is a large sinonasal mass with invasive appearacne. Maxillary sinus and ethmoidal air cells are completely occupied by the mass at the right side and right osteomeatal unit is completely enlarged and obstructed by the mass. Sphenoid and right frontal sinuses also are involved.
Bone destruction is noted at the right maxillary sinus walls and nasal cavity. Right orbit medial wall also has been involved, and the extraconal mass has mass-effect on the right medial rectus with the fat plane between the mass and the muscle intact. No evidence of intracranial extension.
Appropriate histologically investigation confirmed the diagnosis of sinonasal undifferentiated carcinoma.
Sinonasal undifferentiated carcinoma (SNUC) is a rare and highly aggressive neoplasm of the paranasal sinuses and nasal cavity which is characterized by rapid growth, a propensity for locoregional recurrence, distant metastases ( particularly to lung and bone ) , and poor prognosis.
- Pitman KT, Costantino PD, Lassen LF. Sinonasal undifferentiated carcinoma: current trends in treatment. Skull Base Surg. 2011;5 (4): 269-72. Free text at pubmed - Pubmed citation
- Righi PD, Francis F, Aron BS et-al. Sinonasal undifferentiated carcinoma: a 10-year experience. Am J Otolaryngol. 1996;17 (3): 167-71. Pubmed citation