Sister Mary Joseph's nodule - endometrial carcinoma

Case contributed by Ammar Haouimi
Diagnosis almost certain

Presentation

Painful palpable mass of the umbilical region.

Patient Data

Age: 50 years
Gender: Female
  • ovoid mass distending the endometrial cavity hypo- to isointense to normal endometrium on T1, hyperintense on T2 with restricted diffusion and moderate heterogeneous enhancement on postcontrast sequences. Deep myometrial invasion (less than half of the myometrium) mainly of the left posterolateral aspect of the corporeal region. Small intramural leiomyoma (Figo 2)
  • large subumbilical solid/cystic mass extending to the umbilical region (measuring 12 x 11 x 10 cm) with two components:
    • a solid component of anterior location, eliciting a low signal on T1, heterogeneous signal on T2 with restricted diffusion and heterogeneous enhancement on post-contrast sequences
    • a cystic component of low signal on T1, high signal on T2 with no restricted diffusion and peripheral enhancement on post-contrast sequences
  • mild intraperitoneal effusion with nodular thickening and enhancement of the peritoneal reflections and soft tissue nodule (on the right side of the umbilical mass) suggestive of peritoneal carcinomatosis

Case Discussion

MRI features of endometrial carcinoma (histologically proven) with peritoneal carcinomatosis and a Sister Mary Joseph nodule (proven by ultrasound-guided biopsy).

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