Skeletal metastases from breast carcinoma

Case contributed by Dr Nikola Todorovic
Diagnosis almost certain

Presentation

Severe pain. Patient is receiving palliative therapy.

Patient Data

Age: 50 years
Gender: Female

There are diffuse skeletal, predominantly osteolytic lesions, involving the skull, spine, ribs, pelvis and proximal parts of the femur bilaterally.

There are also pathological fractures of the T4 and T10 vertebrae.

Case Discussion

In 2014 the patient was diagnosed with invasive lobular breast carcinoma and underwent tumor removal surgery, as well as radiotherapy and chemotherapy with FAC protocol, which was interrupted because of prolonged pancytopenia.

Bone marrow biopsy showed diffuse metastatic infiltration.

The patient is now on palliative pain therapy and regular outpatient follow-up examinations.

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