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Small bowel angioedema (ACE-inhibitor related)

Case contributed by Michael P Hartung
Diagnosis almost certain

Presentation

Abdominal pain.

Patient Data

Gender: Female

Small right effusion. Mild thickening/hyperenhancement of the jejunum. More pronounced target-like enhancement of the ileum. Small ascites. 

Case Discussion

This patient reported a gradual onset of symptoms after starting an ACE-inhibitor for hypertension 3 days earlier. Symptoms improved rapidly after cessation of the medication without any additional therapy, supporting the diagnosis. This pattern of enhancement is fairly typical for angioedema related to ACE-inhibitor, and is an important diagnosis to keep in mind as it only requires conservative therapy and cessation of the inciting medication rather than more aggressive GI or surgical workup. 

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