Spinal schwannoma

Case contributed by A.Prof Frank Gaillard

Presentation

Back pain

Patient Data

Age: 80 years
MRI

There is a large ovoid mass within the thecal sac extending between the L1 and L3 levels with thick irregular peripheral enhancement. There is some peripheral susceptibility artefact with layering blood products. The upper aspect of the mass abuts the conus. The filum terminale appears to be displaced posterior to the mass, rather than incorporated within it, although this is not certain.

There is mass effect on the adjacent nerve roots which are largely compressed posteriorly and laterally and mechanical compression is evidenced by nerve root redundancy above and below the mass, and prominent of the pial veins. 

Conclusion:

Large intradural mass within the thecal sac with the differential diagnosis of a cystic nerve sheath tumour (schwannoma) and myxopapillary ependymoma. 

Case Discussion

The patient went on to have a resection.

Histology

MICROSCOPIC DESCRIPTION:

Sections show a moderately cellular tumour. It comprises hypercellular areas composed of fascicles of bland spindle shaped cells admixed with loosely textured relatively hypocellular areas. Occasional poorly formed verocay bodies are identified. There are scattered thick walled blood vessels within the tumour. Some scattered tumour cells show mild nuclear pleomorphism. No mitoses or necrosis is identified.

The tumour cells are strongly and diffusely S-100 positive and EMA negative.

The features are of a schwannoma. There are no features suggestive of a myxopapillary ependymoma.

FINAL DIAGNOSIS: spinal schwannoma.

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Case information

rID: 44932
Case created: 9th May 2016
Last edited: 21st Apr 2017
Inclusion in quiz mode: Included

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