Presentation
Non-neutropenic fevers. Background of multiple myeloma.
Patient Data
Age: 80 years
Gender: Female
From the case:
Splenic candidiasis
Axial C+ portal venous phase

Multiple rounded hypoattenuating foci within the spleen (absent on previous abdominal CT performed a fortnight prior). Given that they are new, these could represent underlying infection, with fungal infection to be considered if patient is immunocompromised.
From the case:
Splenic candidiasis
Longitudinal

Spleen span measures 85 mm. Multiple 'target' lesions measuring up to 11 mm in diameter.
Case Discussion
The splenic lesions are likely to be caused by Candida microabscesses. Other fungal infections or neoplastic disease could also cause this appearance.