Splenic thorotrastosis

Case contributed by Dr Rohit Sharma


Previous Thorotrast contrast administration.


Plain abdominal radiograph

Abdominal radiograph shows multiple micronodular hyperdense lesions speckled in the left hypochondrium.


Select illustrative CT non-contrast axial slice

Select illustrative axial slice demonstrates multiple micronodular hyperdense lesions in the spleen.

Case Discussion

In this patient with previous known administration of Thorotrast contrast, findings are in-keeping with splenic accumulation (or thorotrastosis).

Thorotrast is a suspension of radioactive thorium dioxide that was used as a contrast agent until the 1950s. Following administration, it typically accumulates within the body - particularly the liver, spleen, and peripancreatic lymph nodes. Radiographically, it is seen as metallic densities which may have a multinodular, miliary or diffuse pattern of distribution. Due to Thorotrast being an alpha emitter with a very long half-life, it is highly carcinogenic, and thus is no longer in use.


Case uploaded on behalf of and courtesy of Dr Paul McCoubrie.

PlayAdd to Share

Case information

rID: 73597
Published: 16th Jan 2020
Last edited: 16th Jan 2020
Inclusion in quiz mode: Excluded

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.