Splenic tuberculosis (TB)

Case contributed by Dennis Odhiambo Agolah
Diagnosis almost certain

Presentation

Abdominal pains with six months amenorrhea, on implanon.

Patient Data

Age: 30 years
Gender: Female
ultrasound

Diffuse multiple hypoechoic wedge-shaped defects are littered within the entire splenic parenchymal surface that minimally geographically spares island areas of normal splenic parenchyma. There is resultant mild splenic enlargement (current splenic index = 78.1 cm2). Color Doppler imaging reveals insignificant vascularity within the lesions. The rest of the abdominal-pelvic structures grossly looked normal.

Case Discussion

A near miss (with a curvilinear probe) splenetic anomaly during abdominal sonography. Notice how insignificant the tiny lesions almost appear on a curvilinear sector probe, albeit with a change in technique to a high resolution linear sector array transducer, conspicuously pronounces the lesions now unmistakably. No gross abdominal-pelvic lymphadenopathy identified.

In the setting of such heterogenous and multifocal splenic parenchymal lesions, plausible differentials to consider may include 1-7:

  • splenic tuberculosis (hypoechoic small multiple lesions within the splenic parenchyma, likely microabscesses, as in the case above where the patient is being managed for disseminated pulmonary tuberculosis, is on ARV/HIV drugs and is on management for acute kidney infection. The PTB was confirmed with a positive LAM test on a follow-up.

  • multiple splenic infarcts (hypoechoic variable-sized lesions, permeating and void of target appearance)

  • lymphoproliferative splenic disorder (may present with target appearance and with para-aortic/retroperitoneal lymphadenopathy)

  • sarcoidosis (extensive/massive splenomegaly; diffusely heterogenous)

  • Hodgkin's disease and malignant lymphoma [mostly target lesion(s). Should be further supported clinically and/ or with other imaging modalities]

  • other hematological disorders

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