Spontaneous rupture of hepatocellular carcinoma

Case contributed by Chris O'Donnell
Diagnosis certain

Presentation

Known HCC. Sudden onset of severe abdominal pain and hypotension. No trauma.

Patient Data

Age: 85 years
Gender: Male

Large mass at the right hepatic dome with IVC invasion (arrow) typical of HCC with rupture close to the gall bladder fossa and bleeding into the adjacent peritoneal cavity producing a typical sentinel clot sign.

Case Discussion

Although rare, spontaneous rupture and hemorrhage is a recognized complication of HCC. "Sentinel clot sign" is a very important CT sign pointing to the site of bleeding ie clotting occurs at the site of tissue rupture (higher HU of 45 - 60 with heterogeneous appearance) whereas blood that leaks away from the liver remains liquid in the peritoneal cavity (ie layered effect with HU of ~ 40).

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