Squamous cell bronchogenic carcinoma

Case contributed by Associate Professor Natalie Yang

Note: This case has been tagged as "legacy" as it no longer meets image preparation and/or other case publication guidelines.

Right middle and lower zone consolidation with marked enlargement of the right hilum, suggestive of malignancy. 

Right central mass with resultant main middle lobe bronchial compression and atelectasis. Confluous pathological lymph node enlargement in the right hilum and mediastinum. 

Case Discussion

Squamous cell bronchogenic carcinoma

Histology

Bronchial brushings

Malignant cells present. Abnormal cells are seen with delicate cytoplasm, enlarged nuclei, and coarsely granular cytoplasm, consistent with non small cell carcinoma. 

Endobronchial biopsies

Right bronchus intermedius biopsy invasive squamous cell carcinoma, moderately differentiated. 

The clinical history of an obstructing lesion and a right hilar mass is noted.  The specimen consists of multiple fragments of tissue covered by squamous type mucosa.  No normal ciliated bronchial epithelium is identified.  An invasive squamous cell carcinoma is seen underneath the surface mucosa.  

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