Squamous cell carcinoma of urinary bladder

Case contributed by Ahmed Abdrabou
Diagnosis certain


Hematuria and dysuria of two months duration. The patient had bilharziasis a long time ago.

Patient Data

Age: 50 years
Gender: Male

Polypoidal irregular mural thickening of the left lateral and posterior wall of the urinary bladder which coalesce to form large fungating mass arising from left lateral wall are seen and extends through the wall to invade the perivesical fat. It infiltrates also the lower ureteric orifices resulting in bilateral hydronephrosis. Few bilateral internal iliac lymph nodes are noted. Prostatic hypertrophy and Foley catheter are also seen.

Diagnosis: Squamous cell carcinoma of the urinary bladder on top of bilharziasis (histopathology proved)

Case Discussion

Squamous cell carcinoma of the urinary bladder occurs after metaplasia of the urinary bladder epithelium from transitional cell to squamous cell. It can occurs in settings of schistosomaisis, chronic irritation by stones, and chronic infection. 

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