Sub-acute brain infarct

Case contributed by Dr Prashant Mudgal


Middle aged hypertensive female presented with slurred speech and altered sensorium.

Patient Data

Age: 47 years
Gender: Female

Multiple well defined areas which are hypointense on T1 (images not available) and hyperintense on T2, FLAIR and DWI are seen involving  the right cerebral peduncle, splenium of corpus callosum, bilateral thalami and white matter of bilateral fronto-parietal lobes.

There is mild intravascular and cortical enhancement following gadolinium injection.

Imaging features are suggestive of sub-acute infarct.

Case Discussion

Detection of different patterns of contrast enhancement can help in determining the age of infarct. There are two patterns of MR contrast enhancement in the acute phase of ischemic stroke-intravascular enhancement and cortical enhancement.

In a study of evolution of contrast enhancement pattern during first week of acute infarct it is proven that Intravascular enhancement is detectable from day 1  and cortical enhancement starts from day 2 and intensity increases as with the age of infarct during the first week of onset of symptoms1.

After the first few days, there is a well-known phase of parenchymal contrast enhancement caused by leakage of contrast material across the disrupted blood-brain barrier. 


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Case information

rID: 27344
Published: 30th Jan 2014
Last edited: 14th Aug 2019
Tag: pm
Inclusion in quiz mode: Included

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