Subependymal giant cell astrocytoma - tuberous sclerosis

Case contributed by Paresh K Desai
Diagnosis almost certain


Headache. History of focal seizures in childhood.

Patient Data

Age: 25 years

Note: This case has been tagged as "legacy" as it no longer meets image preparation and/or other case publication guidelines.

CT reveals a solitary calcified subependymal lesion on body of right lateral ventricle and a hyperdense lesion at the foramen of Monro on left side.

Case Discussion

Patient was being treated for seizure disorder and also had cutaneous manifestations of Tuberous Sclerosis.

There was h/o focal seizures in childhood. The patient also had Shagreen patches and adenoma sebaceum.  MRI done subsequently showed additional cortical tubers.

SGCA is the second most common manifestation of tuberous sclerosis (TS). First being tubers. It affects 5% of patients. The foramen of Monroe is the classic location. Some of the subependymal nodules themselves can transform into SGCA over a period of time.

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