Subependymal grey matter heterotopia

Case contributed by Mostafa Elfeky
Diagnosis almost certain

Presentation

Headache

Patient Data

Age: 40 years
Gender: Female

Brain

mri

Abnormally located gray-matter is seen at the left frontoparietal periventricular region, encircling the frontal horn of the left lateral ventricle, indenting its ependymal lining which is focally ectatic, those gray-matter area shows normal MRI signal at T1 and T2 with no post-contrast enhancement.

Focal thinning of the body of corpus callosum.

Case Discussion

Features are representing unilateral left-sided perifrontal nodular heterotopia accompanied by focal dysgenesis of the body of corpus callosum. Focal unilateral involvement appears as small nodules of grey matter seen immediately deep to the ependymal layer, elevating it and distorting the outlines of the ventricles, resulting in focal ventricular dilatation, not to be confused with closed-lip schizencephaly.

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