Subependymoma: lateral ventricle
Past history of breast cancer.
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MRI of the brain demonstrates a left frontal horn intraventricular mass with intermediate T1 and very high T2 signal. Following administration of contrast only scant enhancement is visible. The mass does not have convincing calcifications and does not have restricted diffusion.
MACROSCOPIC DESCRIPTION: A rubbery ovoid pink nodule 15x8x8mm and six pale tan fragments 2-10mm. Multiple TS through large nodule.
MICROSCOPIC DESCRIPTION: The sections show somewhat lobulated fragments of moderately cellular glial tumour. The tumour cells show prominent clustering. They have round to ovoid nuclei with no significant nuclear pleomorphism. There is microcystic change in the background. No mitoses, endothelial cell hyperplasia or necrosis is identified. No evidence of metastatic carcinoma is seen. The features are those of a subependymoma.
DIAGNOSIS: Right frontal horn tumour: Subependymoma (WHO Grade I).