Submandibular pleomorphic adenoma

Case contributed by Andrew Ryan


Mass in right submandibular gland.

Patient Data

Age: 45 years
Gender: Male

Ultrasound demonstrates a well circumscribed hypoechoic mass in the right submandibular gland, measuring 1.0 x 1.2  x 1.4cm in diameter. Color examination demonstrates prominent internal vascularity.

 Images courtesy of Dr Anthony Upton

FNA mass in right submandibular gland.


The FNA smears show classic features of pleomorphic adenoma:

  • cellular, with single to irregular groups and sheets of epithelial cells
  • interspersed stromal fragments
  • background population of myoepithelial cells - often described as having a 'plasmacytoid' appearance

FNA submandibular gland (pap stain) - The smears show large numbers of epithelial cells interspersed with vaguely fibrillary to whispy stroma. 

Case Discussion



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