Telangiectatic osteosarcoma

Case contributed by Dr Bita Abbasi


An adolescent with lower limb mass

Patient Data

Age: 14
Gender: Female

There is an aggressive lytic lesion in the distal metaphysis of femur. Soft tissue swelling is noted. There are sparse areas of ossification in the tumor matrix. 


There is a multiloculated lytic lesion in the distal meyaphysis of the femur. Multiple fluid-fluid levels are seen in the lesion. Massive edema is seen in the muscular compartments. Bone marrow edema involves the epiphysis. Multiple hemorrhagic areas are seen in the T1 W image. 

The findings are consistent with telangiectatic osteosarcoma.

Case Discussion

Telangiectatic osteosarcoma is an uncommon variant of osteosarcoma that consists of multiple blood-filled cavities. The location and age-distribution of the lesion are like conventional osteosarcoma. 

In plain X-ray the lesion appears as a lytic destructive lesion with minor amounts of matrix mineralization or periosteal reaction. 

In MRI the lesion contains of multiple cysts filled with blood with multiple fluid-fluid level areas. These findings are not specific and might as well be seen in giant cell tumor and aneurysmal bone cyst

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Case information

rID: 42045
Published: 3rd Jan 2016
Last edited: 13th Mar 2016
Inclusion in quiz mode: Included

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