Testicular seminoma

Case contributed by Dr Bruno Di Muzio


Testicular pain.

Patient Data

Age: 22 years
Gender: Male

Testicular ultrasound

The testicles have normal size and vascularity, showing multiple microcalcifications foci, particularly on the left. Within the upper portions of the left testicle, there is a well-defined 1.1 cm lobulated hypoechogenic nodule that shows increased internal vascularity, but no cystic or calcified components. The epididymides have normal sonographic appearances. No hydrocoele.  

Case Discussion

Given the images appearances, a testicular tumour was sought, particularly seminoma, and the patient was referred to the urology clinic. CT staging of the chest, abdomen and pelvis was unremarkable. Tumour markers were negative.The patient underwent left orchiectomy, which has revealed seminoma. 


MACROSCOPIC DESCRIPTION: "Left testicle": A testis 45x32x25mm with spermatic cord 90mm in length x up to 18mm in width. The tunica vaginalis is soft and movable. Inked green. In the upper pole of the testis there is a firm white vaguely lobulated tumour 12mm in maximum dimension. The tumour is clear of the tunica albuginea, the rete testis and the epididymis. The background testis is soft, homogeneous and orange. 

MICROSCOPIC DESCRIPTION: Sections show testis containing a well circumscribed unencapsulated tumour. The tumour is composed of nests and cords of cells set within a retracted stroma. The malignant cells are large and have irregularly shaped nuclei with coarse chromatin, variably prominent nucleolus, and eosinophilic cytoplasm. The tumour stroma contains a brisk infiltrate of lymphocytes. The tumour is 12mm in maximum dimension, and well clear of the tunica albuginea, rete testis and epididymis. The surrounding testicular parenchyma shows tubular atrophy and intratubular germ cell neoplasia. The tumour is completely excised, and the spermatic cord margin is clear.

DIAGNOSIS: Left orchidectomy: Seminoma. - 12mm in maximum dimension. - clear of spermatic cord margin. - clear of tunica albuginea, rete testis and epididymis.

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Case information

rID: 53925
Case created: 14th Jun 2017
Last edited: 17th Jun 2017
System: Urogenital
Tag: rmh
Inclusion in quiz mode: Included

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