Testicular seminoma

Case contributed by Dr Bruno Di Muzio


Testicular pain.

Patient Data

Age: 22 years
Gender: Male

Testicular ultrasound

The testicles have normal size and vascularity, showing multiple microcalcifications foci, particularly on the left. Within the upper portions of the left testicle, there is a well-defined 1.1 cm lobulated hypoechogenic nodule that shows increased internal vascularity, but no cystic or calcified components. The epididymides have normal sonographic appearances. No hydrocoele.  

Case Discussion

Given the images appearances, a testicular tumor was sought, particularly seminoma, and the patient was referred to the urology clinic. CT staging of the chest, abdomen and pelvis was unremarkable. Tumor markers were negative.The patient underwent left orchiectomy, which has revealed seminoma. 


MACROSCOPIC DESCRIPTION: "Left testicle": A testis 45x32x25mm with spermatic cord 90mm in length x up to 18mm in width. The tunica vaginalis is soft and movable. Inked green. In the upper pole of the testis there is a firm white vaguely lobulated tumor 12mm in maximum dimension. The tumor is clear of the tunica albuginea, the rete testis and the epididymis. The background testis is soft, homogeneous and orange. 

MICROSCOPIC DESCRIPTION: Sections show testis containing a well circumscribed unencapsulated tumor. The tumor is composed of nests and cords of cells set within a retracted stroma. The malignant cells are large and have irregularly shaped nuclei with coarse chromatin, variably prominent nucleolus, and eosinophilic cytoplasm. The tumor stroma contains a brisk infiltrate of lymphocytes. The tumor is 12mm in maximum dimension, and well clear of the tunica albuginea, rete testis and epididymis. The surrounding testicular parenchyma shows tubular atrophy and intratubular germ cell neoplasia. The tumor is completely excised, and the spermatic cord margin is clear.

DIAGNOSIS: Left orchiectomy: Seminoma. - 12mm in maximum dimension. - clear of spermatic cord margin. - clear of tunica albuginea, rete testis and epididymis.

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Case information

rID: 53925
Published: 16th Jun 2017
Last edited: 14th Aug 2019
System: Urogenital
Tag: rmh
Inclusion in quiz mode: Included

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