Found with left facial droop, left hemiparesis. GCS initially 15 but subsequently decreased. Past history of alcohol abuse.
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Deep right sided acute intracerebral haematoma, with its epicentre in the thalamus. The haemorrhage extends into the intraventricular system. There is no subarachnoid haemorrhage.
The haemorrhage displaces the third ventricle slightly, and there is hydrocephalus of the lateral and third ventricles.
Severe generalised cerebral volume loss. Moderate periventricular low attenuation in keeping with small vessel change. Central gliosis within the pons may represent previous central pontine myelinosis or a chronic ischaemic infarct.
The patient died 10 days after the ICH and underwent a post mortem. This showed a large haematoma centred in the right thalamus, which extends into the ventricular system.
There is significant small and large vessel cerebrovascular disease, with lipohyalinosis and arteriolosclerosis in the white matter, plus enlarged perivascular spaces. Central cystic area of degeneration in the pons consistent with previous central pontine myelinosis. Immunohistochemistry shows no significant amyloid angiopathy.
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- Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. (2010) The Lancet. Neurology. 9 (7): 689-701. doi:10.1016/S1474-4422(10)70104-6 - Pubmed