Thalassemia - hair on end sign

Case contributed by Abdulmajid Bawazeer
Diagnosis certain

Presentation

Known case of thalassemia major with dizziness and headache.

Patient Data

Age: 30 years
Gender: Male

Gross thickening of diploic space of the skull vault with no discrete masses.

No intracranial masses, hemorrhage or vascular thrombosis.

Case Discussion

The 'hair on end' sign is always appreciated on lateral skull radiograph and CT. In this case, it is evident on MRI. As in the above case, it is related to thalassemia major.

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