Thalassaemia: with hair on end sign

Case contributed by Dr Nauman Akram


A young girl with the known thalassemia

Patient Data

Age: 12
Gender: Female

Radiograph skull Lateral view demonstrates widened diploic space and vertical striations running perpendicularly giving rise to the characteristic hair on end appearance.

Case Discussion

Hair on end appearance refers to the radiologic pattern of elongated trabeculae in widened diploic space which represent as calcified spicules perpendicular to the bone surface, corresponding to a periosteal reaction to disturbed bone, calvarial thickening and thinning of the inner table; classically seen in children and adolescents with hemolytic anemias such as thalassemia.

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Case information

rID: 54519
Case created: 13th Jul 2017
Last edited: 14th Jul 2017
Inclusion in quiz mode: Included

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