Toxic thyroid adenoma (thyroid scintigraphy)

Case contributed by Arshdeep Sidhu
Diagnosis probable


Fatigue and weight loss.

Patient Data

Age: 60 years
Gender: Female

Thyroid Scintigraphy

Nuclear medicine

Anterior images show elevated Tc99m-pertechnetate uptake in a specific focal area of the left thyroid lobe (red arrow) relative to the extra-nodular thyroid tissue (yellow arrow), which demonstrates decreased (partial suppression) or absent (complete suppression) uptake due to decreased TSH levels. Salivary gland (arrowhead) is barely visualized secondary to decreased background activity.

Case Discussion

A hot (hyperfunctioning) nodule on thyroid scintigraphy is a characteristic finding in toxic thyroid adenoma. Not all nodules are toxic, and some cases may present as euthyroid. Radiotracer uptake is focal, unlike in Graves disease.

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.