Transient lesion of the splenium

Case contributed by Dr Nick Tarasov



Patient Data

Age: 25
Gender: Male

There is oval T2-hyperintense and T1-iso-hypointense focus located at the splenium of the corpus corpus callosum, demonstrating high DWI signal with corresponding low ADC values. The remainder of the brain is unremarkable. No susceptibility artefact seen on T2*.

Case Discussion

This patient has no neurological deficit. There are many possible aetiologies for transient splenial callosal lesions. This may include:

  • hypernatremia
  • hypoglycemic encephalopathy
  • bacterial or viral meningoencephalitis
  • hemolytic uremic encephalopathy
  • posterior reversible encephalopathy syndrome (PRES)
  • radiation therapy
  • diffuse axonal injury
  • Marchiafava–Bignami disease
  • cerebral infarction
  • epilepsy
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Case information

rID: 39837
Case created: 22nd Sep 2015
Last edited: 29th May 2016
Inclusion in quiz mode: Included

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