Transverse myelitis - temporal evolution

Case contributed by Mohamed Saber
Diagnosis almost certain

Presentation

Acute bilateral lower limbs weakness with foot drop.

Patient Data

Age: 55 years
Gender: Female

Initial study

mri

MRI study shows mild patchy signal changes of the distal spinal cord presents as intramedullary abnormal T2 hyperintensity with minimal swelling

Follow-up after 4 days

mri

MRI study shows distal spinal cord long segment (4-5 vertebral levels) of signal alteration presents as a striking abnormal T2 hyperintensity with evident cord swelling. The disease is severe enough to involve most of the cross-sectional area of the cord

Case Discussion

Normal MRI doesn't exclude transverse myelitis as up to 40% of cases have no findings on MRI 1. In the early acute stage, the signal changes of the cord may be mild and questionable however, in the subacute stage, the cord changes appear evidently.

In this case, the neurologist's diagnosis according to the patient's history and examination was severe transverse myelitis secondary to acute viral infection, that was not correlated with the MRI except lately. Radiologists should be aware of this to avoid exclusion or underestimation of the cord disease, they should correlate with the clinical data as well

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