Tuberous sclerosis

Case contributed by Ammar Haouimi
Diagnosis almost certain

Presentation

Epilepsy.

Patient Data

Age: 2 years
Gender: Male
mri
  • innumerable small subependymal nodules (hamartomas) along the wall of the lateral ventricles of high signal to the grey matter on T1, iso-to low signal on T2 and FLAIR with no enhancement on postcontrast sequences. Some of them show a low signal on GE (calcified nodules)

  • multiple bilateral cortical and subcortical areas of low signal on T1, high signal on T2 and FLAIR with no enhancement on postcontrast sequences in keeping with cortical/subcortical tubers.

  • tiny cysts in the white matter arround the trigones mainly on the left with surrounding abnormal high signal on FLAIR and T2, representing probably a cystic degeneration

Case Discussion

The clinical presentation and MRI features are most consistent with tuberous sclerosis.

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