Tuberous sclerosis

Case contributed by Prashant Mudgal


Young patient presented with seizures.

Patient Data

Age: 9 years
Gender: Male

Multiple corticle and subcortical tubers are noted in bilateral frontal, parietal and occipital regions. These tubers appear hyperintense on T2 and FLAIR. In addition to that, there are multiple subependymal calcified hamartomatous nodules noted on the outer walls of bilateral lateral ventricles, showing blooming on SWI sequence. The imaging features are suggestive of tuberous sclerosis.

Case Discussion

Tuberous sclerosis is a rare genetic disease that involves various organs in the body and CNS being one of the most common site. Typical brain involvement characteristic features are cortical and subcortical tubers, white matter abnormalities, subependymal hamartomas and giant cell astrocytomas.

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.