Tuberous sclerosis with subependymal giant cell astrocytoma

Case contributed by Dr Amro Omar

Presentation

Seizures , mental retardation

Patient Data

Age: 12

MRI demonstrates a large lobulated intensely enhancing mass arising from the left foramen of Monro causing mild hydrocephalus. Please note the subependymal nodules (best appreciated in susceptibility weighted sequences), and the subtle hyperintensities in the occipital lobe representing an nice example of cortical/subcortical tubers of tuberous sclerosis (best appreciated in FLAIR).

Same patient four years earlier

Case Discussion

Subependymal giant cell astrocytoma is

  • WHO grade I , it is
  • The most common CNS neoplasm in Tuberous sclerosis (up to 15% of patients with TSC , rarely (if ever) arises in absence of Tuberous sclerosis)
  • Typically occurs during 1st two decades
PlayAdd to Share

Case Information

rID: 36589
Case created: 30th Apr 2015
Last edited: 1st Oct 2015
Inclusion in quiz mode: Included

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.