Tubular adenoma of the breast

Case contributed by Dr Ammar Ashraf


Left breast lump for one year. No pain, fever, or nipple discharge.

Patient Data

Age: 25 years
Gender: Female

A well-defined oval-shaped isoechoic mildly heterogeneous mass lesion is seen in the upper outer quadrat (2 o'clock position) of the left breast.  A few small cystic areas are seen in it. No calcifications or posterior acoustic shadowing is seen. Sonographic features are suggestive of a benign bresat lesion,like fibroadenoma.

Case Discussion

Procedure: Ultrasound-guided Tru-Cut biopsy of the left breast mass, followed by the left breast lumpectomy with complete excision.

Diagnosis: Benign fibroepithelial lesion suggestive of tubular adenoma.

Comment: The immunostain with the antibody anti-p63 and CK high molecular weight is diffusely positive.

Tubular adenoma (TA) of the breast, is a rare benign encapsulated tumor of the breast. It is closely related to the fibroadenoma of the breast and cannot be differentiated on imaging due to overlapping imaging features. Histologically, it is composed of densely packed ductal structures lined by epithelial and myoepithelial cells with scant connective tissue component, which helps in differentiating it from fibroadenoma.

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