Type I lissencephaly

Case contributed by A.Prof Frank Gaillard


Neonate with abnormal neurology.


Axial slice of non-contrast CT head shows grossly underformed gyri, a smooth cortical surface, band heterotopia and dilated lateral ventricles, more prominent posteriorly (temporal horns) and right more than left. The findings are compatible with lissencephaly type I.


Head ultrasound (HUS) demonstrates the same findings seen on the CT head.

Case Discussion

Typical appearance of lissencephaly type I, with no normal gyration visible, lending a figure 8 appearance to the cortex.

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Case information

rID: 10595
Published: 24th Aug 2010
Last edited: 16th Dec 2019
Inclusion in quiz mode: Included

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