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Unilateral periventricular nodular heterotopia

Case contributed by Dr Imran Ahmad Khan


Long history of epilepsy.

Patient Data

Age: 40 years
Gender: Female

MRI brain

Selected images demonstrate an ovoid well defined focal lesion is seen abutting the frontal horn of left lateral ventricle. The lesion is isointense to cortical grey matter on all sequences. There is no surrounding white matter edema. A thin CSF intensity line is seen radiating from the lesion towards the adjoining cortex, likely representing a prominent perivascular space.

Case Discussion

The patient has history of complex partial seizures from past 15 years. EEG has shown abnormal discharges in the left fronto-temporal region.  

MRI brain shows focal unilateral grey matter heterotopia in left frontal region. No other associated anomaly was seen. 

Seizures are seen in 80-90% cases of grey matter heterotopia.

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Case information

rID: 83197
Published: 18th Oct 2020
Last edited: 18th Oct 2020
Inclusion in quiz mode: Included

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