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US-guided thyroid nodule FNA

Case contributed by Craig Hacking
Diagnosis certain

Presentation

Nodular thyroid gland.

Patient Data

Age: 35 years
Gender: Female
ultrasound

Right thyroid isoechoic nodule. Several passes with a 25G FNA needle.

Case Discussion

FNA Histology

FNA right thyroid:

The specimen is highly cellular containing groups of follicular cells arranged in predominantly, repetitive micro-follicles. Some follicular cells are found in crowded clusters with overlapping and mildly enlarged nuclei, nuclear pleomorphism and focal grooves. The background consists of blood and scant thick colloid.

SUMMARY

FNA right thyroid: Suggestive of a follicular neoplasm (Category 4).

Right thyroidectomy histology

Right hemithyroidectomy - stitch upper pole: The right hemithyroidectomy specimen shows a large nodule with well-circumscribed fibrosis around it. The features are that of an adenoma. There is no evidence of capsular or vascular invasion. The sections also reveal the presence of two foci of micropapillary carcinoma, measuring 6 mm and 5 mm in maximum dimension in sections 1E and 1J. There appear to be two benign parathyroid glands identified. There is also a separate larger hyperplastic nodule in section 1L.

SUMMARY

Right thyroidectomy: micropapillary carcinoma

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