Presentation
Whole-body MRI follow-up for known P53 mutation.
Patient Data
Bilateral small areas of spiculated high STIR signal in the subcutaneous fat of both anterolateral thighs, stable since last MRI a year ago.
In the subcutaneous fat of both anterolateral thighs, there are hypoechogenic nodules with surrounding hyperechogenic fat.
Case Discussion
Typical location, stability over time, patient age and imaging features are in keeping with post-vaccination aluminum granulomas which are caused are thought to be caused by aluminum-containing adjuvants in certain vaccines. These can cause local pruritus. Treatment is purely symptomatic and development of these granulomas is not a contraindication to further vaccination with the offending vaccine or other types.