Vermian metastasis and subependymoma

Case contributed by Assoc Prof Frank Gaillard



Case Discussion

Final Diagnosis: 

  • A. Brain, fourth ventricular region: Subependymoma.
  • B. Cerebellum, vermis: Metastatic adenocarcinoma - colon.
Microscopic Description: 

A. Sections show a relatively sparsely cellular tumor characterized by small clusters and short linear profiles of tumor cells with bland round nuclei, within a fibrillar glial background. Areas if necrosis, vascular neogenesis, significantly increased cellularity or elevated mitotic activity, are not seen. 

B. Sections show small fragments of cerebellar tissue containing metastatic carcinoma showing features consistent with metastatic adenocarcinoma, likely of colonic origin. Tumor necrosis is evident.

5 years earlier: Terminal ileum and right colon resection showing well-differentiated adenocarcinoma of the cecum/ascending colon

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Case information

rID: 5218
Published: 18th Dec 2008
Last edited: 13th Aug 2019
Tag: mets
Inclusion in quiz mode: Included

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