Young-onset Alzheimer disease

Case contributed by Chee Kok Yoon

Presentation

56 years old Chinese female, presented with working memory impairment for 6 years associated with catastrophic reaction, occasional depressive mood, loss of sense of direction, no psychosis. Cognitive assessment showed very severe memory impairment (non-verbal>verbal) and severe executive function impairment.

Patient Data

Age: 56
Gender: Female
mri

The hippocampi are atrophied, more so than the rest of the brain. No focal lobar atrophy. Posterior fossa unremarkable. 

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