Zebra lines

Case contributed by Dr Jeremy Jones


History of cyclical bisphosphonate therapy


The bones of the ankle and foot are abnormal with increased sclerosis.

Features are of osteopetrosis.

In addition, there are multiple transverse sclerotic lines (zebra lines) projected across the distal metaphysis that are the result of cyclical bisphosphonate therapy.

Case Discussion

This young patient's distal tibia and fibula demonstrate multiple horizontal sclerotic bands, the zebra stripe sign, as a result of cyclical bisphosphonate therapy.

There is background osteopetrosis.

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Case information

rID: 8067
Published: 6th Jan 2010
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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