Zollinger Ellison syndrome

Case contributed by Dr Jake Ball


Abnormal gastroscopy findings

Patient Data

Age: 65 years
Gender: Female

Multiple arterial hyperenhancing lesions within the duodenum and pancreas with diffuse mucosal thickening of the stomach.


Nuclear medicine

The arterial enhancing lesions on the CT demonstrate dotatate avidity. It is also noted that the stomach is intensely avid.  A liver metastasis is also demonstrated. 

Case Discussion

Multiple hormonally active neuroendocrine tumors (gastrinomas) produce an excess of the gastrin hormone that causes stomach to produce too much acid. There is an associated Multiple Endocrine Neoplasia 1 syndrome (PiPanPar).

Gastrinomas are the most common type of Neuroendocrine tumor and it is thought up to 90% arise from the Gastrinoma triangle;

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.