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Fontan procedure

The Fontan procedure is a repair surgical strategy for congenital cardiac anomalies. It is not usually used in isolation, but in combination with other repair procedures in a staged manner in an attempt to correct the underlying cardiac pathology. Rationale The procedure attempts to bypass the...

Foramen ovale (cardiac)

The foramen ovale (or ovalis) is the opening in the interatrial septum in the fetal heart that allows blood to bypass the right ventricle and non-ventilated lungs, shunted from the right atrium to the left atrium. Specifically it represents the opening between the upper and lower portions of the...

Fossa ovale

The fossa ovale (or ovalis) is the small oval depression in the interatrial septum at the site of the closed foramen ovale, which closes once fetal circulation ceases in the first few minutes of postnatal life. It represents the overlapping primary and secondary septa of the interatrial septum. ...

Four chamber cardiac view (fetal)

The four chamber cardiac view is an important and routinely performed view in both fetal echocardiography as well as on a standard second trimester anatomy scan. Detectable pathology The four chamber view can only detect some of the congenital cardiac anomalies (~64% according to one study 2) ...

Fractional flow reserve

Fractional flow reserve (FFR) is a technique to evaluate the haemodynamic relevance of coronary artery stenoses 1,2,. It is defined as "the ratio of maximal flow achievable in the stenotic coronary artery to the maximal flow achievable in the same coronary artery if it was normal" 1 . FFR has b...

Gerbode defect

The Gerbode defect describes a rare abnormal left-to-right shunt between the left ventricle and right atrium through a defect in the atrioventricular septum, usually congenital in etiology. Epidemiology Gerbode defects are rare congenital cardiac anomalies, and are thought to account for less ...

Glenn shunt

The Glenn shunt, also known as Glenn procedure, is a palliative surgical procedure for a variety of cyanotic congenital heart diseases. Rationale In this procedure, the systemic venous return is re-directed to the pulmonary circulation, bypassing the right heart 1-3. It can be used in a varie...

Glycogen storage disease type II

Glycogen storage disease type II, also known as Pompe disease or acid maltase deficiency disease, is an inherited lysosomal disorder characterised by abnormal glycogen accumulation within lysosomes. It is a multi-system disorder involving the heart, skeletal muscle and liver. It is caused by the...

Great cardiac vein

The great cardiac vein (GCV) runs in the anterior interventricular groove and drains the anterior aspect of the heart where it is the venous complement of the left anterior descending artery. It is the main tributary of the coronary sinus. Gross anatomy It begins on the anterior surface of th...

Haemochromatosis (cardiac manifestations)

Cardiac involvement in haemochromatosis typically occurs with primary haemochromatosis, as the organ is usually spared in the secondary form of the disease. For a general discussion, and for links to other system specific manifestations, please refer to the article on haemochromatosis. Epidem...

Haemopericardium

Haemopericardium refers to the presence of blood within the pericardial cavity, i.e. a sanguineous pericardial effusion. If enough blood enters the pericardial cavity, then a potentially fatal cardiac tamponade can occur. Pathology Etiology There is a very long list of causes 1,4 but some of...

Heart

The heart is a hollow, muscular organ of the middle mediastinum, designed to pump oxygenated blood around the systemic circulation and de-oxygenated blood around the pulmonary circulation Gross anatomy The heart has a somewhat conical form and is enclosed by pericardium. It is positioned poste...

Heart chambers

There are four heart chambers, the right atrium, left atrium, right ventricle and left ventricle. These receive blood from the body and lungs and contract to transmit blood to the lungs for oxygenation and to the body for use in metabolism. It is best to list the four chambers in order of the s...

Heart failure (summary)

This is a basic article for medical students and other non-radiologists Heart failure is a syndrome of cardiac ventricular dysfunction, where the heart is unable to pump sufficiently to meet the body's blood flow requirements. Clinical presentation Although it is useful to divide the signs an...

Heyde syndrome

Heyde syndrome is an association between aortic valve stenosis and gastrointestinal hemorrhage. The etiology of the gastrointestinal bleeding in this setting is uncertain, but it is thought to be related to intestinal angiodysplasia. The strength of this association independent of age-related d...

Hibernating myocardium

Hibernating myocardium is myocardial tissue that has reduced contractility due to poor perfusion, but remains viable. It is important as hibernating myocardium can recover normal contractility with revascularisation. Pathology Hibernating myocardium is most commonly seen in the setting of chr...

High-output cardiac failure

High output cardiac failure refers to a state of cardiac failure that is associated with a higher than normal cardiac output which is still not sufficient for body tissue demands. Clinical presentation Patients can present with a number of symptoms of varying degrees which include tachycardia,...

HIV/AIDS (cardiovascular manifestations)

Cardiovascular manifestations are seen with increased frequency in the HIV/AIDS adult population, and include: pericardial effusions dilated cardiomyopathy (prevalence 8-30%) endocarditis: either infective or non-bacterial thrombotic (marantic) which is associated with malignancy or HIV wasti...

Hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is a type of cardiomyopathy and is the leading cause of sudden death (from arrhythmias) in infants, teenagers and young adults. Terminology Although hypertrophic cardiomyopathy can generally describe a hypertrophied and non-dilated left ventricle due to any ca...

Hypoplastic left heart syndrome

Hypoplastic left heart syndrome (HLHS) is a cyanotic congenital cardiac anomaly where affected individuals can have profound cyanosis and cardiac failure. It is one of the commonest causes for a neonate to present with congestive cardiac failure and the 4th most frequent cardiac anomaly to mani...

Hypoplastic right heart syndrome

Hypoplastic right heart syndrome is a congenital cardiac anomaly. It is characterised by an underdeveloped right side of the heart, including the right ventricle, tricuspid valve, pulmonary valve, and pulmonary arteries. Epidemiology It may be present in around 1.1% of stillbirths and is rarer...

Idiopathic dilated cardiomyopathy

Idiopathic dilated cardiomyopathy is a subtype of dilated cardiomyopathy. It is a type of non-ischemic cardiomyopathy where no underlying cause can be found. Epidemiology This form of cardiomyopathy may account for up to 50% of all dilated cardiomyopathies 4. Patients usually ranging around 20...

Idiopathic hypereosinophilic syndrome

Idiopathic hypereosinophilic syndrome (IHES) is a leukoproliferative disorder and refers to a situation when there is an unexplained prolonged eosinophilia with associated organ system dysfunction. The condition can affect several organ systems which includes: heart: cardiac involvement in idio...

Idiopathic pulmonary arterial hypertension

Idiopathic pulmonary arterial hypertension is uncommon, representing only a tiny fraction of all cases of pulmonary arterial hypertension, which has a very long list of secondary causes (see causes of pulmonary arterial hypertension). Terminology Older terms for this entity include primary pul...

IgG4-related cardiovascular disease

IgG4-related cardiovascular disease is one of the many manifestations of IgG4-related disease and may present as: aortitis and periaortitis arteritis and periarteritis of small to medium-sized arteries coronary arteritis and periarteritis inflammatory aneurysms pericarditis

Implantable loop recorder

Implantable loop recorders, also known as insertable cardiac monitors, are small insertable devices that continuously monitor and record cardiac rhythms. They are placed subcutaneously and used for the evaluation of patients with recurrent unexplained episodes of palpitations or syncope. They sh...

Increased cardiothoracic ratio (summary)

This is a basic article for medical students and other non-radiologists Increased cardiothoracic ratio describes widening of the cardiac silhouette on a chest radiograph. This is only of use when making an assessment of a PA chest x-ray since the AP chest x-ray causes the artefactual magnificat...

Infective endocarditis

Infective endocarditis is defined as infection of the endocardium. It commonly affects the valve leaflets and chordae tendineae, as well as prosthetic valves and implanted devices. Epidemiology Infective endocarditis has an estimated general prevalence of 3 to 9 cases per 100,000. Intravenous ...

Inferior aortic recess

The inferior aortic recess is one of the pericardial recesses forming a small space within the pericardium, which arises from the transverse pericardial sinus between the ascending aorta and the left atrium. It extends inferiorly to the level of the aortic valve. It may mimic mediastinal lympha...

Inferior interventricular artery

The inferior interventricular artery (also known as the posterior interventricular artery or posterior descending artery, PDA) is an artery that extends along the inferior interventricular sulcus. The artery supplies the posterior third of the interventricular septum through posterior septal per...

Inferior mediastinum

The inferior mediastinum is the box-shaped space in the mediastinum below the transthoracic plane of Ludwig between the wedge-shaped superior mediastinum above and the diaphragm and inferior thoracic aperture below. There are no physical structures that divide the superior and inferior mediastin...

Innervation of the heart

The heart has extrinsic and intrinsic innervation, which allows the heart to continue beating if the nerve supply to the heart is disrupted (e.g. in cardiac transplant). The heart receives innervation from both the superficial and deep cardiac plexuses, which have both parasympathetic (from vag...

Interarterial course of the left coronary artery

An inter-arterial course of the left coronary artery is defined as origination of the left main or left anterior descending coronary artery from the right coronary sinus of Valsalva, with a course between the ascending aorta and the pulmonary artery trunk. Terminology An inter-arterial course...

Inter-arterial course of the right coronary artery

Inter-arterial course of the right coronary artery (RCA), also known as a malignant variant, may occur if the right coronary artery has an aberrant origin from the the left coronary sinus. It is an uncommon anomaly with potential risk of cardiac ischemia. When the right coronary artery arises a...

Interatrial septal aneurysm

Interatrial septal aneurysm or atrial septal aneurysm (ASA) is defined as an abnormal protrusion of the interatrial septum. The exact length of the protrusion that defines an interatrial septal aneurysm varies in the literature, ranging from >11 mm to >15 mm beyond normal excursion in adults 4,5...

Interventricular septal aneurysm

Interventricular septal aneurysm is different from ventricular aneurysm which usually occurs in the cardiac apex. It is defined as a bowing of the interventricular septum of more than 15 mm on either side in adults and 5 mm in children during normal cardiac motion. It may involve either the memb...

Intra-aortic balloon pump

Intra-aortic balloon pumps (IABP) are used in the intensive care setting to provide haemodynamic assistance to patients in cardiogenic shock. Function and physiology The device is comprised of a catheter introduced via a femoral artery sheath, which extends retrogradely to the proximal descend...

Intra-atrial course of the right coronary artery

Intra-atrial course of the right coronary artery is an uncommon anatomic variation in the course of the right coronal artery, usually involving the mid and distal segments, where the vessel partially or completely courses through the right atrial chamber. It is usually asymptomatic and clinical...

Intracardiac thrombi

Intracardiac thrombi are seen in a variety of clinical settings and can result in severe morbidity or even death from embolic events. They can occur following myocardial infarction with ventricular thrombus formation, or with atrial fibrillation and mitral stenosis where atrial thrombi predomina...

Intraventricular

Intraventricular is a term used to denote lesions / processes that occur within either the ventricles of the brain or the ventricles of the heart. In both cases, most lesions actually arise from the surrounding brain parenchyma / heart muscle and grow exophytically into the ventricles. See a...

Iron overload cardiomyopathy

Iron overload cardiomyopathy (IOC) refers to a secondary form of cardiomyopathy resulting from the accumulation of iron in the myocardium. It occurs mainly due to genetically determined disorders of iron metabolism (e.g. cardiomyopathy in haemochromatosis, thalassaemia 6,7) or multiple transfusi...

Isomerism

Isomerism is a term which in general means 'mirror-image'. It is used in the context of heterotaxy and is of two types: left isomerism right isomerism Left isomerism Mirror image of the structures on the left side of the chest along the left-right axis of the body, i.e. patients with isomeri...

Jaffe-Campanacci syndrome

Jaffe-Campanacci syndrome is characterised by: multiple non-ossifying fibromas of the long bones and jaw café au lait spots intellectual disability kyphoscoliosis hypogonadism or cryptorchidism ocular malformations cardiovascular malformations giant cell granuloma of the jaw History and...

Kawasaki disease

Kawasaki disease is a small to medium vessel vasculitis predominantly affecting young children. It can affect any body organ but there is a predilection for the coronary vessels. Epidemiology Japan has the highest incidence in the world, with an annual incidence of 300/100,000 children under t...

Kawashima procedure

Kawashima procedure is a palliative surgical procedure performed in cases of: left isomerism and azygos continuation of the inferior vena cava single functional ventricle single atrium and common atrioventricular valve with or without regurgitation pulmonary stenosis It is performed by crea...

Keshan disease

Keshan disease is a selenium-deficient condition characterised primarily by a dilated cardiomyopathy, resulting in congestive cardiac failure, cardiomegaly, and, on occasion, fulminant cardiogenic shock. It most commonly presents in young children and menstruating women. Historically it was ori...

Kommerell diverticulum

Kommerell diverticula occur in some anomalies of the aortic arch system. It usually refers to the bulbous configuration of the origin of an aberrant left subclavian artery in the setting of a right-sided aortic arch. However, it was originally described as a diverticular outpouching at the origi...

Kounis syndrome

Kounis syndrome, also known as allergic acute coronary syndrome, refers to an acute coronary syndrome accompanying mast cell activation from allergic, hypersensitivity, or anaphylactoid reactions. Pathology It is represented by a vasospastic acute coronary syndrome with or without the presence...

Labelled imaging anatomy cases

This article lists a series of labelled imaging anatomy cases by system and modality. Brain CT head: non-contrast axial CT head: non-contrast coronal CT head: non-contrast sagittal CT head: angiogram axial CT head: angiogram coronal CT head: angiogram sagittal MR head: T2 axial MR head:...

Lambl’s excrescence

Lambl’s excrescences, also known as valvular strands, are small, filiform, fibrous strands located on cardiac valves. Epidemiology Thought to be present in 70-80% of adults according to pathological studies, but only ~40% on echocardiograph studies 1. When present, multiple Lambl’s excrescence...

LCx and LAD arising separately from the left coronary sinus

One of the anatomical variants of coronary artery origin comprises the left circumflex coronary artery (LCx) and left anterior descending coronary artery (LAD) arising separately from the left coronary sinus. Hence there is no common left main coronary artery (LCA/LMCA). As there is no vascular...

Leadless cardiac pacemaker

Leadless cardiac pacemakers are a recently introduced type of cardiac conduction device. These pacemakers are self-contained right ventricular single-chamber pacemakers that are implanted percutaneously via a femoral approach 1-3. There are currently two leadless cardiac pacemakers on the market...

Left anterior descending artery

The left anterior descending (LAD) artery, also known as the anterior interventricular branch, is a branch of the left coronary artery. Gross anatomy It descends along the inteventricular groove. It can be divided into proximal, mid and distal segments and this helps to differentiate the nam...

Left atrial aneurysm

Left arterial aneurysms refer to rare focal outpouchings arising from the left atrium. They can be congenital or acquired. Congenital left atrial aneurysms can be further divided into intra- and extra-pericardial types. Clinical presentation Patients may be asymptomatic or present with atrial ...

Left atrial appendage

The left atrial appendage (LAA) (a.k.a. left auricle) is a pouch-like projection from the main body of the left atrium, which lies in the atrioventricular sulcus in close proximity to the left circumflex artery, the left phrenic nerve, and the left pulmonary veins. Gross anatomy Morphological ...

Left atrial appendage closure devices

Left atrial appendage (LAA) closure devices are implantable cardiac devices which are placed in the left atrial appendage for stroke prevention in patients with atrial fibrillation who have contraindications to pharmacological anticoagulation. Depending on the device they may be inserted percuta...

Left atrial diverticulum

A left atrial diverticulum (LAD) refers to a pouch-like structure with a saclike shape with a broad-based ostium and a smooth contour to its body. They are considered an anatomical variant. Complications some suggest that there may be a possible latent relationship between LA diverticulum and...

Left atrial enlargement

Left atrial enlargement may result from many conditions, either congenital or acquired. It has some characteristic findings on a frontal chest radiograph. CT or MRI may also be used for diagnosis. Clinical presentation An enlarged left atrium can have many clinical implications, such as: Ortn...

Left atrial line

The left atrial (LA) line monitors LA pressure and is indicative of left ventricular function, preload and afterload. The LA line enters from the left superior vein and exits the far side of the chest. The LA line is a single lumen catheter unlike the right atrial line, which is double lumen. N...

Left atrium

The left atrium is one of the four chambers of the heart. It receives oxygenated blood from the pulmonary circulation that is then delivered to the left ventricle and then into the systemic circulation. Gross anatomy The left atrium is grossly cuboidal, and like the right atrium has an appenda...

Left circumflex arising from right coronary sinus

Left circumflex (LCx) arising from right coronary sinus (RCA) is a coronary arterial variant. Epidemiology It is considered the most common coronary anomaly with prevalence range of around 0.37-0.7% of all patients. Course It commonly arises from a separate ostium within the right sinus, or ...

Left main coronary artery

The left main coronary artery (LMCA) or left coronary artery (LCA) is one of the two main arteries that supply the heart with oxygenated blood. Gross anatomy Origin It is a branch of the ascending aorta, with its normal origin in the left aortic sinus, just superior to the aortic valve 1-2. ...

Left pulmonary venous recess

The left pulmonary venous recess is one of the pericardial recesses forming a small space within the pericardium. It arises from the pericardial cavity proper located between the left superior and inferior pulmonary veins, posterior to the left atrium. It invaginates towards the oblique pericard...

Left pulmonic recess

The left pulmonic recess is one of the pericardial recesses forming a small space within the pericardium, which arises from the transverse pericardial sinus. It is located posterior to the pulmonary trunk and left pulmonary artery. It may mimic mediastinal lymphadenopathy or a bronchogenic cyst.

Left-sided superior vena cava

A left-sided superior vena cava (SVC) is the most common congenital venous anomaly in the chest, and in a minority of cases can result in a right-to-left shunt 3-4. Epidemiology A left-sided SVC is seen in 0.3-0.5% of the normal population and in ~5% of those with congenital heart disease 3. I...

Left ventricle

The left ventricle is one of four heart chambers. It receives oxygenated blood from the left atrium and pumps it into the systemic circulation via the aorta. Gross anatomy The left ventricle is conical in shape with an anteroinferiorly projecting apex and is longer with thicker walls than the ...

Left ventriclular false tendon

Left ventricular false tendons, also known as left ventricular muscular bands, are fibromuscular structures that arise from the inner trabeculated myocardial layer of the left ventricle. They may have different lengths and thicknesses. Epidemiology The incidence of false tendons ranges from 18...

Left ventricular aneurysm

Left ventricular aneurysms are discrete, dyskinetic areas of the left ventricular wall with a broad neck (as opposed to left ventricular pseudoaneurysms), thus often termed true aneurysms. Epidemiology True left ventricular aneurysms develop in less than 5% of all patients with ST-elevation my...

Left ventricular assist device

Left ventricular assist devices (LVAD) are surgically implanted devices that aid pumping blood in patients with severe refractory cardiac failure. It may be used as a bridge to cardiac transplantation, or as destination therapy in patients who are not a transplant candidate. Principle The LVAD...

Left ventricular diverticulum

True diverticuli of the left ventricle refer to congenital anomalies affecting the left ventricle. Epidemiology The condition typically occurs in children and is thought to occur in around 0.4% of cases based on autopsy studies. Clinical presentation In isolated cases, they are often asympto...

Left ventricular ejection fraction (echocardiography)

Left ventricular ejection fraction is a surrogate for left ventricular global systolic function, defined as the left ventricular stroke volume divided by the end-diastolic volume. Terminology Point-of-care echocardiography protocols typically use a semi-quantitative approach in defining the ej...

Left ventricular enlargement

Left ventricular enlargement can be the result of a number of condition, including: pressure overload hypertension aortic stenosis volume overload aortic regurgitation mitral regurgitation wall abnormalities left ventricular aneurysm hypertrophic cardiomyopathy Radiographic features P...

Left ventricular mass index

Left ventricular mass index (LVMI) is a parameter used in echocardiography cardiac MRI. LVMI is calculated using the following equations: LVMI = LVM (left ventricular mass/body surface area left ventricular mass = 0.8{1.04[([LVEDD + IVSd +PWd]3 - LVEDD3)]} + 0.6 Where LVEDD = LV end-diast...

Left ventricular outflow tract

The left ventricular outflow tract (LVOT) is considered represent the region of the left ventricle that lies between the anterior cusp of the mitral valve and the ventricular septum. Its dimensions are often recorded in the TAVI work up studies. Related pathology left ventricular outflow trac...

Left ventricular outflow tract view (fetal echocardiogram)

The left ventricular outflow tract (LVOT) view (or five chamber view) is one of the standard views in a fetal echocardiogram. It is a long axis view of the heart, highlighting the path from the left ventricle into the ascending aorta (left ventricle outflow tract). In this view the right ventr...

Left ventricular pseudoaneurysm

Left ventricular pseudoaneurysms are false aneurysms that result from contained myocardial rupture, and are a rare complication of a myocardial infarction (MI). They should not be confused with left ventricular aneurysms, which are true aneurysms containing all the layers (endocardium, myocardiu...

Libman-Sacks endocarditis

Libmann-Sacks endocarditis (LSE), also known as verrucous endocarditis, is a form of nonbacterial thrombotic endocarditis characterised by large thrombi vegetations over the endocardial surface. It was considered the predominant form of endocarditis in systemic lupus erythematosus (SLE) until tr...

Lipomatous hypertrophy of the inter-atrial septum

Lipomatous hypertrophy of the interatrial septum (LHIS) is a relatively uncommon disorder of the heart characterised by benign fatty infiltration of the interatrial septum. It is commonly found in elderly and obese patients as an asymptomatic incidentally discovered finding. Epidemiology The ...

Lipomatous metaplasia of the myocardium

Lipomatous metaplasia of the myocardium is a phenomenon where there is fat deposition within the myocardium. It is often seen following a myocardial infarction but can also rarely been seen in conditions such as arrhythmogenic right ventricular dysplasia. Pathology The exact etiology of lipoma...

Lutembacher syndrome

Lutembacher syndrome refers to the association of an atrial septal defect (ASD) with mitral stenosis. Both the defects can be either congenital or acquired. History and etymology It is named after Rene Lutembacher 4.

Lyme disease

Lyme disease, also known as borreliosis, is a condition caused by the bacteria Borrelia burgdorferi, with infection being via the ixodid tick. Terminology Controversy around Lyme disease centres on chronic infection with some author doubting its existence 3. There are some terms that help dif...

Major aortopulmonary collateral arteries

Major aortopulmonary collateral arteries (MAPCAs) are persistent tortuous fetal arteries that arise from the descending aorta and supply blood to pulmonary arteries in the lungs usually at the posterior aspect of hilum. Pathology Embryologically, the intersegmental arteries regress with the no...

Marfan syndrome

Marfan syndrome is a multisystem connective tissue disease caused by a defect in the fibrillin 1 gene. Cardiovascular involvement with aortic root dilatation and dissection is the most feared complication of the disease. Epidemiology The estimated prevalence is around 2-6 per 100,000 2,5. Ther...

McConnell's sign (echocardiography)

The McConnell's sign describes a regional pattern of acute right ventricular dysfunction on transthoracic echocardiography first observed in a cohort of patients with acute pulmonary thromboembolism. In contrast to the global wall motion abnormalities observed in chronic right ventricular dysfun...

Mediastinum (ITMIG classification)

The International Thymic Malignancy Interest Group (ITMIG) classification of mediastinal compartments was developed to reflect a division of the mediastinum based on cross-sectional imaging. It was in part an effort to consolidate prior discrepant classification systems in use by different medic...

Medical devices in the thorax

Medical devices in the thorax are regularly observed by radiologists when reviewing radiographs and CTs. Extrathoracic devices tubing, clamps, syringes lying on or under the patient rubber sheets, foam mattresses, clothing, hair braids, nipple piercings etc. may also be visible These devices...

Metabolic syndrome

The metabolic syndrome, also known as syndrome X, is a set of five conditions, which together increase a patient's risk of developing cardiovascular disease 1. Clinical presentation There are five central components of the metabolic syndrome: hyperinsulinaemia impaired glucose tolerance dys...

Middle cardiac vein

The middle cardiac vein or posterior interventricular vein is a vein of the heart which accompanies the posterior interventricular artery. It courses in the posterior interventricular groove and drains directly into the coronary sinus close to it’s termination. It drains the posterior wall of bo...

Milking effect

Milking effect phenomenon is a pathognomonic angiographic finding in myocardial bridging of coronary arteries. Systolic compression of coronary vessels with partial or complete decompression during diastole is described as milking effect. Its significance lies in: increased risk of thrombus fo...

Miminally invasive direct coronary artery bypass

Minimally invasive direct coronary artery bypass (MIDCAB) is a novel method for bypassing diseased coronary arteries that can replace open coronary artery bypass grafts (CABG) in certain situations, most commonly when bypassing the left anterior descending artery (LAD) with a left internal thora...

Mitraclip device

A MitraClip™ is a device for percutaneous mitral valve repair. It is a percutaneous edge-to-edge attachment system that mimics the surgical procedure. This technique creates a tissue bridge between the anterior and posterior leaflets employing one clip deployed through trans-septal catheterisati...

Mitral annular calcification

Mitral annular calcification (MAC) refers to deposition of calcium (along with lipid) in the annular fibrosa of the mitral valve. Epidemiology Annular calcification is seen in up to 35% of elderly patients. It is common in females over 65 years, in those with myxtomatous degeneration of the mi...

Mitral valve

The mitral valve (or bicuspid valve) is one of the four cardiac valves. It is the atrioventricular valve that allows blood to flow from the left atrium to the left ventricle. It opens during diastole and closes during systole. The valve has anterior and posterior leaflets (cusps), the bases of w...

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