Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and edited by countless contributing members over a period of time. A global group of dedicated editors oversee accuracy, consulting with expert advisers, and constantly reviewing additions.

544 results found
Article

Indium-111 OncoScint

Indium-111 OncoScint is a radiopharmaceutical used in SPECT imaging. It is a labelled monoclonal antibody that is directed against TAG-72, which is a tumour-associated antigen associated with ~95% of colorectal carcinomas and 100% of ovarian carcinomas 1,2. Background hepatic uptake limits sensi...
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Infertility

Infertility is common, affecting 15-20% of couples, and is defined as the inability to conceive after one year of unprotected intercourse in the fertile phase of the menstrual cycle 3. It can be due to a variety of both female and male factors, and these are discussed in separate articles: fema...
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Infertility in the exam

It is important to have a systematic way of approaching a case with subfertility in the exam.  Ultrasound is the initial examination of choice. Always say that you would further assess the uterus with 3D ultrasound. You may also say that in my department we would perform a sonohysterogram or HS...
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Inguinal endometriosis

Inguinal endometriosis is an unusual extrapelvic site for endometriosis. Epidiomology The estimated incidence is as around 0.07% among those having endometriosis 4. There is an increased right sided predilection (around 80-90 %of reported cases) 9. Pathology As with endometriosis in general ...
Article

Intramural uterine leiomyoma

Intramural uterine leiomyoma is the most common type of uterine leiomyoma in terms of location. They are centred primarily within the myometrium. A large intramural uterine leiomyoma can, however, have a submucosal or subserosal component. Clinical presentation They are usually asymptomatic; h...
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Intrauterine air

The presence of intrauterine air can sometimes be inferred by tiny internal echoes on ultrasound or foci of very low attenuation at computed tomography (CT). The term encompasses air within the uterine cavity as well as intramyometrial air. It can arise from a number of situations normal postp...
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Intrauterine blood clot

Intrauterine blood clot can result from a number of situations in gravid, non-gravid and postpartum states. It can mimic many other pathologies. Pathology Any condition that predisposes to an intrauterine haemorrhage can potentially result in an intrauterine blood clot. Radiographic features ...
Article

Intrauterine contraceptive device

Intrauterine contraceptive devices (IUCD) are one of the most frequently used methods of contraception throughout the world. It prevents pregnancy by: thinning the endometrial lining preventing sperm motility preventing implantation There are two main types of IUCDs: non-hormonal metallic (...
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Intravenous leiomyomatosis

Intravenous leiomyomatosis (IVLM) is characterised by the extension into venous channels of histologically benign smooth muscle tumour arising from either the wall of a vessel or from a uterine leiomyoma. Terminology Intravenous leiomyomatosis should not be confused with benign metastasising l...
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In utero bowel perforation

In utero bowel perforation results in a chemical peritonitis (meconium peritonitis) from peritoneal leakage of sterile meconium. It can result from many causes which include: intestinal atresias: jejuno-ileal atresia ileal atresia anal atresia in utero intestinal ischaemia underlying gast...
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Invasive mole

Invasive mole is a tumorous growth associated with gestation and falls under the spectrum of gestational trophoblastic disease. Due to their aggressive growth characteristics, invasive moles are considered locally invasive non-metastasising neoplasms. Epidemiology An invasive mole develops in ...
Article

IOTA ultrasound rules for ovarian masses

The International Ovarian Tumour Analysis (IOTA) group ultrasound rules for ovarian masses are a simple set of ultrasound findings that classify ovarian masses into benign, malignant or inconclusive masses. These rules apply to masses that are not a classical ovarian mass (e.g. corpus luteum, en...
Article

Irregular yolk sac

An irregular yolk sac or an abnormally shaped yolk sac is an imaging feature that can be observed in early pregnancy scanning. It may be seen in up to 17% of early pregnancy scans 1. In contrast to an irregular gestational sac, the observation of an irregular yolk sac in not thought to correlate...
Article

Isolated cleft palate

An isolated cleft palate is a type of facial cleft. This is a much rarer occurrence than a cleft lip +/- palate and is thought to represent a different pathological entity. Epidemiology The estimated incidence is at ~1 per 2000-2500 pregnancies 4-5. There may be a slight female predilection 4....
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Isthmic ectopic pregnancy

An isthmic ectopic pregnancy is a sub type of tubal ectopic pregnancy an accounts for ~ 12% of such cases. According to one study the rate of tubal wall disruption was higher than with an ampullary ectopic pregnancy, suggesting that in an isthmic ectopic pregnancy, the trophoblast penetrates the...
Article

IUCD related uterine perforation

IUCD (Intrauterine contraceptive device) related uterine perforations are one of the causes of uterine perforation. It is rare, but a serious complication of an IUCD insertion, and is often clinically silent.  Epidemiology The incidence rate is reported at ~2 in 1000 2. Clinical presentation ...
Article

Juberg-Hayward syndrome

Juberg-Hayward syndrome (JHS), also known as the oro-cranio-digital syndrome, is a rare autosomal recessive syndrome characterised by the association of the following:  growth retardation microcephaly cleft lip and palate minor vertebral and rib anomalies 4 horseshoe kidneys 4 thumb anomal...
Article

Junctional zone

Junctional zone is a region representing the inner myometrium and is a very important imaging feature in pelvic MR imaging for interpretation of various pathologies. In its intact state, it is usually visualised as a low T2 signal layer beneath the endometrium. This low signal intensity is thou...
Article

Juvenile granulosa cell tumour (ovary)

Juvenile granulosa cell tumours of the ovary (JGCT) are a less common subtype of granulosa cell tumour of the ovary (~5% of cases). They are classified as ovarian sex cord / stromal tumours. Epidemiology It typically occurs in premenarchal girls and young women. The mean age of presentation is...
Article

Klinefelter syndrome

Klinefelter syndrome (KS) is a chromosomal anomaly, which in most cases is characterised by 47 chromosomes instead of the usual 46. Epidemiology The estimated incidence is 0.15-0.2% of live births. Clinical presentation the testes are normal prior to puberty and small in post pubertal testes...
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Krukenberg tumour

Krukenberg tumour, also known as carcinoma mucocellulare, refers to the "signet ring" subtype of metastatic tumour to the ovary. The colon and stomach are the most common primary tumours to result in ovarian metastases, followed by the breast, lung, and contralateral ovary. Epidemiology The tu...
Article

Labelled imaging anatomy cases

This article lists a series of labelled imaging anatomy cases by system and modality. Brain CT head: non-contrast axial CT head: non-contrast coronal CT head: non-contrast sagittal CT head: angiogram axial CT head: angiogram coronal CT head: angiogram sagittal MR head: T2 axial MR head:...
Article

Labia majora

The labia majora (singular: labium majus) form the anteroinferior most part of the vulva, they are continuous with the mons pubis anteriorly and the perineum posteriorly. The labia are apposed in the midline forming the, externally-visible, pudendal cleft. Gross anatomy The labia majora have a...
Article

Labia minora

The labia minora (singular: labium minus) are small glabrous cutaneous folds lying between and just superior to the labia majora. At their posterior margin the labia may be conjoined by a thin cutaneous fold of skin, the frenulum of the labia (also known as the fourchette).  At their anterior m...
Article

Large for dates uterus

A large for date uterus is a clinical observation based on uterine fundal height, which may result in referral for ultrasound assessment, usually in mid to late pregnancy.    Causes include: incorrect dates constitutionally large fetus multiple pregnancy fetal macrosomia polyhydramnios ut...
Article

Large loop excision of the transformation zone

Large loop excision of the transformation zone (LLETZ) is a gynaecological procedure. It is currently one of the most commonly used approaches to treat high grade cervical dysplasia - cervical intraepithelial neoplasia.
Article

Leiomyoma of the uterine cervix

Leiomyomas of the uterine cervix are an unusual variation in terms of location for a uterine leiomyoma. Epidemiology They are rare and account for ~5% (range 0.6-10%) of uterine leiomyomas 1,4. Clinical presentation Clinical symptoms of cervical leiomyomas, including hypermenorrhea, dysmenor...
Article

Lethal multiple pterygium syndrome

Lethal multiple pterygium syndrome (LMPS) is a lethal sub type of the multiple pterygium syndrome. Pathology It is primarily characterised by the presence of pterygia (or wings) present in two or more body areas overlying predominantly the large joints. Accompanying joint contractures are almo...
Article

Levator ani

The levator ani, also known as the muscular pelvic diaphragm, is the musculotendinous sheet that forms the majority of the pelvic floor, supports the pelvic viscera, and aids in urinary and faecal evacuation as well as maintaining continence. Gross anatomy The levator ani has three main compon...
Article

Lipiodol

Lipiodol® (also known as ethiodized oil) is an oil-based iodinated contrast medium that was historically used for myelography and hysterosalpingography. It was later superseded by newer, less hazardous, agents, and now is used primarily as a therapeutic agent. Guerbet is now the sole manufacture...
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Longitudinal vaginal septum

A longitudinal vaginal septum is a congenital abnormality of the vagina where a septum divides it into two parallel cavities. Clinical presentation Usually asymptomatic unless obstructed and if obstructed it may cause cyclic pelvic pain. Amenorrhoea may occur if both cavities are obstructed 1....
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Long philtrum

A long philtrum is a clinical or imaging observation where the philtrum (middle part of the upper lip) is longer than normal.  Pathology Associations It can be associated with a number of anomalies which include Aarskog syndrome Cornelia de Lange syndrome  DiGeorge syndrome femoral hypo...
Article

Long umbilical cord

A long umbilical cord has been variably defined. Considering the mean length of the umbilical cord at ~50-70 cm 1, a long cord in absolute terms is usually taken as one that is over 70 cm in length at term 1-3.  Complications increased incidence of umbilical cord knots increased incidence of ...
Article

Lower vaginal atresia

Lower vaginal atresia is a type of vagina atresia where the the lower 3rd of the vagina fails to develop. Clinical presentation Patients may present with primary amenorrhoea with progressive cyclical abdominal pain. Pathology It is usually not considered a type of Mullerian duct anomaly. It ...
Article

Lowe syndrome

Lowe syndrome (also known as the the oculocerebrorenal syndrome of Lowe) is a multi-system disorder characterised by anomalies primarily affecting the eyes, nervous system, and kidneys. Pathology It is an extremely rare, pan-ethnic, x-linked disease, with estimated prevalence in the general po...
Article

Low-lying placenta

Low-lying placenta occurs when the placenta extends into the lower uterine segment and its edge lies too close to the internal os of the cervix, without covering it. The term is usually applied when the placental edge is within 0.5-5.0 cm of the internal cervical os 1. Some alternatively give th...
Article

Low set ears

Low set ears is a descriptive term used to given a depressed or abnormally low positioning of the pinna by two or more standard deviations below the population average. Pathology Associations Low set ears can be associated with a number of anomalies which include aneuploidic / chromosomal sy...
Article

Lymphoma of the uterine cervix

Lymphoma of the uterine cervix is generally uncommon and when it does occur tends to present as cervical involvement with added background multi-organ disease rather than isolated primary cervical lymphoma 1. It is often considered part of the spectrum of uterine lymphoma. Epidemiology In the ...
Article

Macroglossia

Macroglossia means an enlarged tongue. It may be absolute (greater than the 95th centile) or relative (enlarged compared with oral cavity). Pathology Associations Recognised associations include: chromosomal anomalies Down syndrome tends to be a relative macroglossia may also have intermi...
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Male pseudohermaphroditism

Male pseudohermaphroditism (MPH) is a variation of gender development.  Pathology Patients with male pseudohermaphroditism have 46 XY karyotype and may manifest as a female phenotype with various degrees of undervirilization secondary to partial androgen insensitivity.  Causes androgen insen...
Article

Malignant mixed germ cell tumour of the ovary

A malignant mixed germ cell tumour of the ovary is a subtype of ovarian germ cell tumour. These are not to be confused with malignant mixed Müllerian tumours of the ovary. Epidemiology These tumours are rare. They most commonly affect adolescent women of reproductive age 1. Pathology They ar...
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Malignant mixed Mullerian tumour

Malignant mixed Mullerian tumours (MMMTs), sometimes referred to as a carcinosarcoma, are uncommon malignancies that can occur anywhere along the female genital tract. Pathology It is comprised of both epithelial (carcinomatous) and stromal (sarcomatous) components. Implicated risk factors in...
Article

Malignant mixed Mullerian tumour of the ovary

Malignant mixed Mullerian tumours (MMMT) of the ovary, also known as carcinosarcoma of the ovary, are a rare type of mixed ovarian tumour with both epithelial and stromal components. Epidemiology They are very rare and account for less than 1% of all ovarian cancers. Most women are post-menopa...
Article

Malignant mixed Mullerian tumour of the uterus

Malignant mixed Mullerian tumour (MMMT) of the uterus, also known a uterine carcinosarcoma, is the commonest (up to 50%) uterine sarcoma. They are thought to account for 2-8% of all malignant uterine cancers 1-2. The uterus is the commonest site for malignant mixed Mullerian tumours 1.  Patholo...
Article

Malignant neoplasms involving the uterus

Malignant neoplasms involving the uterus account for a significant proportion of all female cancers. They can be classified as: endometrial carcinoma : commonest: >90% of all uterine malignancies endometrioid carcinoma of the uterus: commonest histological type, ~80% papillary serous carcino...
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Malignant ovarian lesions (sonographic features)

Malignant ovarian lesions can have typical sonographic features, and thus ultrasound is the imaging of choice for initial evaluation of suspected ovarian neoplasm. Radiographic features The features of malignant ovarian neoplasm on ultrasonography include: solid tumour mass >10 cm with locul...
Article

Marshall-Smith syndrome

Marshall-Smith syndrome (MSS) is a rare genetic syndrome primarily comprising of the triad of facial dysmorphism, failure to thrive and accelerated osseous maturation 5. Many cases, however, have wider clinical spectrum. Clinical spectrum general overgrowth - fetal macrosomia failure to thri...
Article

Massive ovarian oedema

Massive ovarian oedema (MOO) is a very rare disease characterised by a tumour-like, usually unilateral, enlargement of the ovary.  Epidemiology It characteristically presents in young women ~ 6 to 33 years (mean age ~21 years 4). Clinical presentation Most patients present with intermittent ...
Article

Maternal hydronephrosis in pregnancy

Maternal hydronephrosis in pregnancy often results as a physiological phenomenon due to the presence of the fetus.  Epidemiology It is estimated that up to 90% of women have some degree of asymptomatic dilatation of the renal calyces, the renal pelves and the upper two-thirds of the ureters du...
Article

Mature cystic ovarian teratoma

Ovarian dermoid cyst and mature cystic ovarian teratoma are terms often used interchangeably to refer to the most common ovarian neoplasm. These slow-growing tumours contain elements from multiple germ cell layers and are best assessed with ultrasound.  Terminology Although they have very simi...
Article

Mayer-Rokitansky-Küster-Hauser syndrome

Mayer-Rokitansky-Küster-Hauser syndrome (MRKH) is a congenital anomaly characterised by vaginal agenesis associated with, in the majority of cases, a spectrum of other genitourinary tract abnormalities. MRKH syndrome belongs to class I Mullerian duct anomalies. Two different forms are described...
Article

McKusick Kaufman syndrome

McKusick Kaufman syndrome (MKS) is an autosomal recessive multiple malformation syndrome primarily characterised by hydrometrocolpos - vaginal atresia post-axial polydactyly congenital heart disease
Article

Meconium pseudocyst

Meconium pseudocyst formation is a complication that can occur with meconium peritonitis. Pathology It occurs when the extruded meconium becomes walled off within the peritoneal space. Radiographic features Plain radiograph May be seen as a rim calcified mass within the abdomen. Antenetal ...
Article

Megalencephaly

Megalencephaly (MEG) is a disorder characterised by an abnormally large brain. It is primarily a proliferative disorder of embryonic origin. It may involve all or part of the cerebral hemispheres and can be bilateral or unilateral. It is often associated with polymicrogyria or agyria.  Terminol...
Article

Meigs syndrome

Meigs syndrome is defined as the presence of ascites and pleural effusion in association with a benign, usually solid ovarian tumour. In the vast majority (80-90%) of cases, the primary tumour is an ovarian fibroma. Other primary tumours include:  ovarian fibrothecoma ovarian thecoma granulos...
Article

Mendelson syndrome

Mendelson syndrome or peptic pneumonia refers to acute chemical pneumonitis caused by the aspiration of stomach contents in patients under general anesthesia. Pathology The etiologic agents is believed to be aspiration of acidic stomach contents, other compounds, e.g. bile, may also play a rol...
Article

Menouria

Menouria (Youssef syndrome) is an uncommon condition in which a vesicouterine fistula results in cyclic haematuria. Vesicouterine fistulas are the rarest of all urinary fistulas, accounting for just 4% of all such fistulas 3. It occurs most commonly after cesarean section. Clinical presentation...
Article

Mesomelia

Mesomelia refers to a shortening of the middle (intermediate) portion of a limb.  Pathology Associations mesomelia-synostoses syndrome (MSS) or mesomelic dysplasia with acral synostoses1 Ellis van-Creveld syndrome 2 Robinow syndrome See also rhizomelia
Article

Mesonephric carcinoma of the cervix

Mesonephric carcinoma of the cervix is an extremely  rare histological sub type of cervical cancer. It falls under the sub group of adenocarcinoma of the cervix. This is a slightly confusing entitiy since some authors have used this term as synonymous with clear cell carcinoma of the cervix 6. ...
Article

Metastases to the ovary

Metastases to the ovary are relatively common with a documented incidence of 5-30% of all malignant ovarian masses. These may be incorrectly grouped under Krukenberg tumours, which are signet cell containing tumours that form only 30-40% of all ovarian metastases.   Clinical presentation Ther...
Article

Metastases to the uterine cervix

Metastases to the uterine cervix is an extremely uncommon with near to nothing publications in radiological literature at the time of writing. Generally, invasion of the uterine cervix (i.e. from vaginal and primary uterine malignancies) are excluded in its definition. There have been occasional...
Article

Metastases to the vagina

Metastases to the vagina are more common than primary vaginal malignancies and account for >80% of vaginal tumours. Pathology Metastases usually spread from contiguous sites most commonly, with lymphatic and hematogenous metastases also recognised. Tumors that metastasise to the vagina includ...
Article

Metatropic dysplasia

Metatrophic dysplasia is a rare group of skeletal dysplasia. It is part of the wider category of rhizomelic dwarfism. Disorders in this group include: fibrochondrogenesis lethal metatropic dysplasia (type 2) or hyperchondrogenesis lethal hyperplastic metatropic dysplasia (type 1) Schneckenbe...
Article

Microgenia

Microgenia is a term meaning a small chin. It is somewhat related to but distinct from the term micrognathia which means a small mandible. Pathology Associations Microgenia can be isolated or be associated with a numer of anomalies which include camptomelic dysplasia 1 hydrolethalus Noonan...
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Micrognathia

The term micrognathia essentially means a small mandible. Pathology A small mandible occurs secondary to abnormalities of the first branchial arch which in turn are caused by deficient or insufficient migration of neural crest cells and usually occur around the 4th week of gestation. Associat...
Article

Microphthalmia

Microphthalmia essentially means small eyes. It is characterised by a small eye within a small orbit. It can be unilateral or bilateral. It is sometimes defined as a globe with a total axial length (TAL) that is at least two standard deviations below the mean for age. Pathology Microphthalmia ...
Article

Midfacial hypoplasia

Midfacial hypoplasia is a type of congenital facial anomaly and can be feature of a number of congenital syndromic anomalies. These include: Antley-Bixler syndrome chromosome 1p36 deletion syndrome 2 chromosome 18q deletion syndrome Crouzon syndrome fetal alcohol syndrome fetal valproate s...
Article

Missing IUCD

A missing IUCD is considered when the retrieval strings of certain types of intra-uterine contraception devices cannot be seen on physical examination. The possibilities are expulsion of IUCD migration of IUCD detachment of IUCD thread uterine perforation in IUCD embedded IUCD Ultrasound ...
Article

Mixed gonadal dysgenesis

Mixed gonadal dysgenesis (MGD) is a type of gonadal dysgenesis characterised by gonadal asymmetry, and/or sex chromosomal mosaicism, as well as retained Müllerian ducts. Pathology Depending on the chromosomal composition, patients may have testes and/or streak gonads. Genetics affected indiv...
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Monochorionic monoamniotic twin pregnancy

A monochorionic monoamniotic (MCMA) twin pregnancy is a subtype of monozygotic twin pregnancy.  These fetuses share a single chorionic sac, a single amniotic sac and, in general, a single yolk sac.  Epidemiology It accounts for the minority (~5%) of monozygotic twin pregnancies and ~1-2% of al...
Article

Monochorionic twin pregnancy

A monochorionic twin pregnancy is a type of monozygotic twin pregnancy where the twins share a single chorion. Depending on the sharing of the amnion this can be divided into two types. monochorionic monoamniotic (MCMA) pregnancy: single amnion monochorionic diamniotic (MCDA) pregnancy: two am...
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Mono nostril

A mono nostril falls under the midline facial defects which arise from cleavage anomalies. It can occur as part of many underlying conditions such as holoprosencephaly: particularly alobar holoprosencephaly trisomy 13 Pathology Associations Several other facial anomalies can be associated ...
Article

Monozygotic twin pregnancy

A monozygotic (MZ) twin pregnancy results from the division of single zygote following fertilisation and shares similar genetic materials. These twins are therefore always of the same gender. Epidemiology MZ twins account for approximately 30% of all twin pregnancies 1. The estimated incidence...
Article

Mons pubis

The mons pubis (plural: montes pubis) refers to the rounded protuberant skin-covered soft tissue overlying the symphysis pubis (in both sexes). It is most prominent in adult females. In females it forms the most superior part of the vulva and it is also called the mons Veneris (plural: montes V...
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MR defaecating proctography

MR defaecography is a dynamic study for evaluation of the pelvic floor and pelvic organ prolapse. Phases There are four phases of evaluation: rest squeeze strain (Valsalva) defaecation/evacuation Method of evaluation Many variations in the techniques described below exist. Patient prepa...
Article

MRI reporting guidelines for cervical cancer

MRI reporting guidelines for cervical cancer help maintain uniformity of reports and assessment of important imaging staging criteria. Tumour size The tumour should be measured in three orthogonal planes. Tumours with a maximum diameter >4 cm are usually not amenable to primary radical surgery...
Article

Mucinous carcinoma of the cervix

Mucinous carcinoma of the cervix is an uncommon histological sub type of cervical cancer. It falls under the group of adenocarcinoma of the cervix. Radiographic features Pelvic MRI As a general rule any mucin-producing tumour will produce very high T2 signal 1. An enhancing lesion, irregular...
Article

Müllerian duct

The Müllerian ducts (or paramesonephric ducts) are paired ducts of mesodermal origin in the embryo. They run laterally down the side of the urogenital ridge and terminate at the Müllerian eminence in the primitive urogenital sinus. In the female, they will develop to form the Fallopian tubes, u...
Article

Müllerian duct anomalies

Müllerian duct anomalies (MDAs) are congenital abnormalities that occur when the Müllerian ducts (paramesonephric ducts) do not develop correctly. This may be as a result of complete agenesis, defective vertical or lateral fusion, or resorption failure. Epidemiology MDAs are estimated to occur...
Article

Müllerian duct anomaly classification

The Müllerian duct anomaly classification is a seven point system that can be used to describe a number of embryonic Müllerian duct anomalies: class I: uterine agenesis / uterine hypoplasia a: vaginal (uterus: normal / variety of abnormal forms) b: cervical c: fundal d: tubal e: combined ...
Article

Mullerianosis

Mullerianosis is a rare type of choristoma, in which normal Mullerian-derived structures (endometrium, endosalpinx, and endocervix) are ectopically located in another organ (e.g. the bladder) through a developmental anomaly. Mullerianosis differs from endometriosis in that at least two types of ...
Article

Multiple pterygium syndrome

The multiple pterygium syndrome(s) (MPS) refers to a group of disorders which are collectively characterised by multiple soft tissue webs (or pterygia) across the neck and various joints. They can be broadly classified into two main groups lethal multiple pterygium syndrome non lethal multipl...
Article

MURCS association

MURCS association refers to the combination of: MU: Müllerian duct aplasia R: renal aplasia /renal agenesis CS: cervicothoracic somite dysplasia See also Mayer-Rokitansky-Kuster-Hauser syndrome
Article

Mushroom cap sign

Mushroom cap sign is one of the important signs of deep rectosigmoid endometriosis seen on T2 weighted MRI sequence. It indicates the submucosal involvement in rectosigmoid region. Radiographic appearance MRI Hypertrophic muscularis propria appears as heterogeneous low signal intensity surrou...
Article

Myometrial cysts

Myometrial cysts are cysts seen in the myometrium and these can be differentiated appropriately based on location and sonological or Doppler features. Pathology Aetiology They can arise from variable aetiology and include. adenomyosis: the cysts are most often seen in the endomyometrial junc...
Article

Myxoid degeneration of a leiomyoma

Myxoid degeneration of a leiomyoma is one of the rarer types of degeneration that can occur in a standard uterine leiomyoma. This term is related but not identical to the term myxoid uterine leiomyoma.  Epidemiology While this type of degeneration is generally considered rare. The higher end o...
Article

Myxoid uterine leiomyoma

Myxoid uterine leiomyomas are a relatively rare pathological subtype of uterine leiomyomas. Terminology They are not to be confused with myxoid degeneration of a uterine leiomyoma which is a different entity. Pathology Myxoid leiomyomas contain abundant myxoid material between smooth muscle ...
Article

Nabothian cyst

Nabothian cysts, also known as a retention cysts of the cervix 11, are non-neoplastic cystic lesions that occur in relation to the uterine cervix. Epidemiology They are common and some reports suggest that they may be seen in up to 12% of routine pelvic MRI scans 2. Clinical presentation The...
Article

Naegele's formula

The Naegele's formula is simple arithmetic method for calculating the EDD (estimated date of delivery) based on the LMP (last menstrual period). To the date of the first day of the LMP (e.g. 22nd June 2008): add seven days (i.e 29th) subtract 3 months (i.e March) add one year (i.e 2009)
Article

Narrow fetal thorax

A narrow fetal thorax on antenatal ultrasound can be present with a number of anomalies which include: achondrogenesis camptomelic dysplasia homozygous achondroplasia Jarcho-Levin syndrome Jeune syndrome - asphyxiating thoracic dysplasia Russell-Silver dwarfism short rib polydactyly syndr...
Article

Neu-Laxova syndrome

Neu-Laxova syndrome is a lethal autosomal recessive multiple malformation syndrome with a heterogeneous phenotype. Clinical presentation The clinical spectrum can be quite wide and includes: dermal / cutaneous severe skin restriction ichthyosis decreased fetal movement marked intrauterine...
Article

Neural tube defects

Neural tube defect (NTD) refers to the incomplete closure of the neural tube in very early pregnancy.  The neural tube comprises of a bundle of nerve sheath which closes to form brain at the anterior end and spinal cord at the posterior end. The closure should occur at around the 28th day of co...
Article

Non gestational choriocarcinoma

Non-gestational choriocarcinoma is choriocarcinoma occurring in the absence of a preceding gestation.  As opposed to a gestational choriocarcinoma, this is a much rarer situation. Pathology In women they often tend to occur in ovary. Most ovarian non-gestational choriocarcinomas occur in mixed...

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