Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and edited by countless contributing members over a period of time. A global group of dedicated editors oversee accuracy, consulting with expert advisers, and constantly reviewing additions.

338 results found
Article

2005 WHO histological classification of odontogenic tumours

The 2005 WHO histological classification of odontogenic tumours lays out a classification system for neoplasms and other tumours related to the odontogenic apparatus. At the time of writing (2016), it is still the most widely used classification system.  Classification Malignant tumours odont...
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2008 WHO classification of tumours of haematopoietic and lymphoid tissues

The 2008 WHO classification of tumours of haematopoietic and lymphoid tissues is at the time of writing (mid 2016) the most widely used classification system.   Classification Hodgkin lymphoma nodular lymphocyte predominance classical Hodgkin lymphoma nodular sclerosing mixed cellularity ...
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2014 WHO classification of endometrial stromal tumours

Endometrial stromal tumours (EST) constitute <2% of all uterine tumours and <10% of uterine mesenchymal neoplasms 1.  Over the past four decades, EST classification has gone through various modifications, starting from the earliest study by Norris and Taylor 2. This was primarily due to the rar...
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Acinic cell carcinoma (lung)

Acinic cell carcinoma of the lung (also known as a Fechner tumour) is a type of lung carcinoma of the salivary gland type. It is extremely rare, especially when it presents in the form of primary acinic cell carcinoma. Pathology Histologically, they are comprised of clear cells with abundant g...
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Acute airspace opacification with lymphadenopathy (differential)

Acute airspace opacification with lymphadenopathy is a subset of the differential diagnosis for generalised airspace opacification and includes: post-obstructive causes (usually chronic, but 'new' changes can occur) primary lung cancer pulmonary metastases lymphoma/leukaemia infection pri...
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Adenocarcinoma (urinary bladder)

Adenocarcinoma of the urinary bladder is rare and accounts for only ~1% of all bladder cancers (90% are transitional cell carcinomas). Pathology Metaplasia of urinary bladder induced by chronic irritation or infection can lead to adenocarcinoma. Pathological types of adenocarcinoma of the urin...
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Adenocarcinoma in situ of the lung

Adenocarcinoma in situ (AIS) of the lung refers to a relatively new entity for a pre-invasive lesion in the lung. This entity partly replaces the noninvasive end of the previous term bronchoalveolar carcinoma. Adenocarcinoma in situ is defined as a localised adenocarcinoma of <3 cm that exhibits...
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Adenocarcinoma in situ, minimally invasive adenocarcinoma and invasive adenocarcinoma of lung

Adenocarcinoma in situ, minimally invasive adenocarcinoma and invasive adenocarcinoma of the lung are relatively new classification entities which replace the now-defunct term bronchoalveolar carcinoma (BAC). In 2011 the International Association for the Study of Lung Cancer (IASLC) and several...
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Adenocarcinoma of the duodenum

Duodenal adenocarcinoma is the most common primary malignancy of the duodenum. Epidemiology Adenocarcinoma is the most common primary malignant neoplasm of the duodenum. It represents 0.3% of all gastrointestinal malignancies and accounts for  50-70% of small bowel adenocarcinomas occurring ei...
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Adenocarcinoma of the lacrimal glands

Adenocarcinoma of the lacrimal glands is rare, with few cases reported in the literature since it was first described in 1996 1. Primary adenocarcinoma of the lacrimal gland is extremely rare; only 9 cases have been reported in the literature 1,2. It can be classified into high- and low-grade ma...
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Adenocarcinoma of the lung

Adenocarcinoma of the lung is one of the non-small cell carcinomas of the lung and is a malignant tumour with glandular differentiation or mucin production. This tumour exhibits various patterns and degrees of differentiation, including lepidic, acinar, papillary, micropapillary, and solid with ...
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Adenoid cystic carcinoma

Adenoid cystic carcinomas are a rare histological subtype of adenocarcinoma. Pathology Adenoid cystic carcinomas are generally considered low grade 4. The tumours have a notable tendency for perineural spread. Location They have a wide distribution and mainly occur in relation to the airways...
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Adenoid cystic carcinoma of lung

Adenoid cystic carcinoma (ACC) of the lung is a type of non-small cell lung cancer. They are classified under lung carcinomas of the salivary gland type. Primary occurrence in the lung parenchyma is rare, while in the thorax they occur more commonly as adenoid cystic carcinoma of the tracheobron...
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Adenoid cystic carcinoma of the breast

Adenoid cystic carcinoma (ACC) of the breast is a rare subtype of breast cancer. Epidemiology They account for only 0.1-0.4% of all breast cancers. Pathology The tumour demonstrates a strikingly characteristic microscopic pattern similar to that of adenoid cystic carcinoma of the salivary gl...
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Adenoid cystic carcinoma of the salivary glands

Adenoid cystic carcinoma (ACC) of the salivary glands is the most common malignancy involving the minor salivary glands and the second most common malignancy involving the parotid gland. Pathology Adenoid cystic carcinomas arise more commonly in the minor salivary glands (~55%) than in the maj...
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Adenoid cystic carcinoma of the tracheobronchial tree

Adenoid cystic carcinomas of the tracheobronchial tree are a type of low-grade tracheal tumour. They are considered to be the second most common primary tumour of the trachea. Epidemiology They are usually first recognised in patients in their 4th and 5th decades. There is no recognised gender...
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Adenomatoid odontogenic tumour

Adenomatoid odontogenic tumours are rare and differ from most other dentition related lesions in that they more frequently occur in the maxilla. Epidemiology They are also seen more frequently in females, most frequently in the second decade of life. Radiographic features They present as an ...
Article

Adenosquamous carcinoma (cervix)

Adenosquamous cell carcinoma (ASC) of the cervix is a rare histological subtype of cervical carcinoma. Pathology It has components of both cervical adenocarcinoma and cervical squamous cell carcinoma. Prognosis An adenosquamous histology appears to be an independent predictor of poor outcome...
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Adenosquamous carcinoma of lung

Adenosquamous carcinoma (ASC) of the lung is a rare type of non-small cell lung cancer. Epidemiology It is thought to constituting 0.4-4% of cases non-small cell lung cancer. Pathology The definition of adenosquamous carcinoma indicates a carcinoma showing components of adenocarcinoma and sq...
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Adrenal calcification

Adrenal calcification is not a rare finding in healthy asymptomatic people and is usually the result of previous haemorrhage or tuberculosis. Addison's disease patients only occasionally have calcification.  Pathology Aetiology Haemorrhage sepsis: Waterhouse-Friderichsen syndrome blunt abdo...
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Adrenal collision tumour

An adrenal collision tumour or collision tumour of the adrenal gland is an uncommon condition where two histologically distinct tumours abut each other or are in close proximity in the same adrenal gland. Pathology Collision tumours have been reported in nearly every organ, for example, collis...
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Adrenal haemangioma

Adrenal haemangiomas are rare benign tumours that are usually incidentally identified (one example of an adrenal incidentaloma). Its significance mainly relates to the difficulty in differentiation from other malignant lesions.  Epidemiology Although these can be found at any age, they are mos...
Article

Adrenal metastases

Adrenal metastases are the most common malignant lesions involving the adrenal gland. Metastases are usually bilateral but may also be unilateral. Unilateral involvement is more prevalent on the left side (ratio of 1.5:1). Epidemiology They are present at autopsy in up to 27% of patients with ...
Article

Adult cervical lymphadenopathy (differential)

Cervical lymphadenopathy in an adult can result from a vast number of conditions. They include: malignancy metastases  from head and neck tumours lymphoma other neoplastic lesions Castleman disease Kaposi sarcoma infection bacterial infection viral infection Epstein-Barr virus herpes...
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AFP elevation

Human alpha fetoprotein (AFP) elevation may occur in a vast number of conditions: liver tumours (hepatocellular carcinoma, hepatoblastoma) <10 ng/ml is within normal limits >20 ng/ml is above normal limits but has low specificity for tumor since it may occur in a setting of diffuse liver inju...
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Ameloblastoma

Ameloblastomas are locally aggressive benign tumours that arise from the mandible, or, less commonly, from the maxilla. Usually present as a slowly but continuously growing hard painless lesion near the angle of the mandible in the 3rd to 5th decades of life, which can be severely disfiguring if...
Article

Anal cancer

Anal cancer is a relatively uncommon malignancy. It accounts for less than 2% of large bowel malignancies and 1-6% of anorectal tumours (~1.5% of all gastrointestinal tract malignancies in the United States 14).  Epidemiology There may be a slight male predilection where its incidence has been...
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Anatomy curriculum

The anatomy curriculum is one of our curriculum articles and aims to be a collection of articles that represent the core anatomy knowledge for radiologists and imaging specialists. General anatomy Neuroanatomy Head and neck anatomy Thoracic anatomy Abdominal and pelvic anatomy Spinal anat...
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Angiosarcoma of breast

Breast angiosarcomas are a rare vascular breast malignancy. Epidemiology As primary tumours of the breast, they account for ~0.04% 2 of all breast cancers and tend to occur in younger women, in their 3rd to 4th decades. Secondary angiosarcoma has an estimated incidence of ~0.09-0.16% and occur...
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Anterior mediastinal mass in the exam

Getting a film with an anterior mediastinal mass in the exam is one of the many exam set-pieces that can be prepared for. The film goes up and after a couple of seconds pause, you need to start talking: CXR There is a left sided mediastinal mass that makes obtuse angles with the mediastinal c...
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Architectural distortion in mammography

Architectural distortion is a mammographic descriptive term in breast imaging. It may be visualised as tethering or indentation of breast tissue.  Pathology Architectural distortion per se is not a mass. It is often due to a desmoplastic reaction in which there is focal disruption of the norma...
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Asbestosis

Asbestosis refers to later development of diffuse interstitial fibrosis secondary to asbestos fibre inhalation and should not be confused with other asbestos related diseases. Epidemiology Asbestosis typically occurs 10-15 years following the commencement of exposure to asbestos and is dose re...
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Assessment of thyroid lesions (general)

Assessment of thyroid lesions is commonly encountered in radiological practice. Thyroid mass hyperplastic / colloid nodule / nodular hyperplasia: 85% adenoma follicular: 5% others: rare carcinoma papillary: 60-80% of carcinomas follicular: 10-20% medullary: 5% anaplastic: 1-2% thyroi...
Article

Asymmetrical density in mammography

Asymmetrical mammographic density is a mammographic morphological descriptor. It is given when there is increased density in one of the breasts, on either one or both standard mammographic views but without evidence of a discrete mass. An asymmetrical density can be further characterised as: ma...
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Atypical ductal hyperplasia

Atypical ductal hyperplasia (ADH) is a histologically borderline lesion that has some, but not all the features of ductal carcinoma in situ (DCIS). Sometimes the distinction between ADH and DCIS is simply on the basis of the number of ducts involved.  Pathology Atypical ductal hyperplasia is a...
Article

Autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD), also sometimes more vaguely referred to as "adult polycystic kidney disease", is as the name would suggest, a hereditary form of adult cystic renal disease.  Epidemiology Autosomal dominant polycystic kidney disease is one of the most commo...
Article

Bat wing opacities (lungs)

Bat's wing or butterfly pulmonary opacities refer to a pattern of bilateral perihilar shadowing. It is classically described on a frontal chest radiograph but can also refer to appearances on chest CT 3-4. Differential diagnosis Bat's wing pulmonary opacities can be caused by: pulmonary oedem...
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Benign and malignant characteristics of breast lesions at ultrasound

Benign and malignant characteristics of breast lesions at ultrasound allow the classification as either malignant, intermediate or benign based on work published by Stavros et al in 1995. Radiographic features Ultrasound Malignant characteristics (with positive predictive values) sonographic...
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Benign metastasising tumours

There are a number of benign metastasising tumours: benign metastasising meningioma 1,2 benign metastasising leiomyoma 3 primary adenoma of thyroid 4 giant cell tumour of bone 5
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Bethesda criteria of hereditary non-polyposis colorectal cancer

The Bethesda criteria are an alternative to the Amsterdam criteria for the clinical diagnosis of hereditary non-polyposis colorectal cancer (HNPCC).  Diagnosis of HNPCC is made if any of the following criteria are fulfilled: Amsterdam criteria are met 2 or more HNPCC related malignancies  pa...
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BI-RADS IV

A BIRADS IV lesion under the breast imaging reporting and data system refers to a suspicious abnormality. BIRADS IV lesions may not have the characteristic morphology of breast cancer but have a definite probability of being malignant. A biopsy is recommended for these lesions. If possible, the ...
Article

Bilateral testicular lesions

Bilateral testicular lesions have a relatively limited differential diagnosis.  Neoplastic  lymphoblastic leukemia (acute or chronic) lymphoma (non-Hodgkin's) primary testicular lymphoma is rare but the testes are often the site of lymphoma/leukemia recurrence due to the chemoptherapy inabil...
Article

Blastic plasmacytoid dendritic cell neoplasm

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare haematological malignancy. It was previously termed as blastic natural-killer lymphoma or agranular CD4+ natural killer cell leukemia. Epidemiology It only represent a wel small propotion (around 0.44%) of all haematological malign...
Article

Bone lesions with sequestrum

There are several bony lesions that can involve or depict a sequestrum. They include: Common brodie abscess: osteomyelitis Less common eosinophilic granuloma certain soft tissue tumours (with bony extension)  malignant fibrous histiocytoma lymphoma metastasis (especially from breast ca...
Article

Bone marrow

Normal bone marrow is divided into red and yellow marrow, a distinction made on the grounds of how much fat it contains. Gross anatomy Red marrow is composed of: haematopoietic cells supporting stroma reticulum (phagocytes and undifferentiated progenitor cells) scattered fat cells a rich ...
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Bony sequestrum (mnemonic)

Mnemonics to help remember common causes of bony sequestrum include: E-FILM LIFE FILE Mnemonics E-FILM E: eosinophilic granuloma  F: fibrosarcoma I: infection (Brodie abscess) L: lymphoma (skeletal)  M: malignant fibrous histiocytoma or metastasis (especially from breast carcinoma) LI...
Article

Borderline ovarian serous cystadenoma

Borderline ovarian serous cystadenomas lie in the intermediate range in the spectrum of ovarian serous tumours and represent approximately 15% of all serous tumours. Epidemiology They present at a younger age group 1-2 than the more malignant serous cystadenocarcinomas with a peak age of prese...
Article

Brachytherapy

Brachytherapy, also known as sealed source radiotherapy or endocurietherapy, is a form of radiotherapy where a radioactive source is placed, under the guidance of imaging, within or next to the area requiring treatment. Brachytherapy is commonly used to treat localised prostate cancer, breast c...
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Brain abscess

Brain abscess is a potentially life threatening condition requiring rapid treatment, and prompt radiological identification. Fortunately, MRI is usually able to convincingly make the diagnosis, distinguishing abscesses from other ring enhancing lesions.  Epidemiology Demographics reflect at-ri...
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Brain tumours in infancy

Common brain tumours in infancy (i.e. under one year of age) are quite different from those of brain tumours in adulthood: intracranial teratoma (germ cell tumour) primitive neuroectodermal tumour (CNS-PNET) medulloblastoma (SHH and Group 3) choroid plexus papilloma anaplastic astrocytoma ...
Article

Breast abscess

A breast abscess is a relatively rare but significant complication of mastitis that may occur during breastfeeding, particularly in primiparous women. The clinical context is a key to diagnosis as imaging appearances (particularly ultrasound) can mimic many other entities such as breast carcinom...
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Breast imaging-reporting and data system (BIRADS)

BIRADS classification is proposed by American College of Radiology, last updated in November 2015, and is widely used classification system at the time of writing this article (July 2016). The BIRADS acronym stands for Breast Imaging-Reporting and Data System which is a widely accepted risk ass...
Article

Breast lymphoma

Breast lymphoma refers to involvement of the breast with lymphoma and may be primary or secondary. Epidemiology Both primary and secondary breast lymphoma are rare accounting for ~ 0.5% (range 0.3-1.1%) of all breast malignancies. Clinical presentation Breast lymphoma may present either as a...
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Breast MRI

Breast MRI is the most sensitive method for detection of breast cancer. Depending on international health regulations, it is either applied for screening of women at high risk for developing breast cancer (e.g. BRCA-1 and BRCA-2 carriers), as an additional diagnostic test in pretherapeutic breas...
Article

Bright rim sign in dysembryoplastic neuroepithelial tumours

The bright rim sign has been described in dysembryoplastic neuroepithelial tumours (DNETs) and is seen, as the name so aptly describes, as a rim of high signal around the DNET on FLAIR sequences.
Article

Bulging duodenal papilla

Major duodenal papilla is a conic or cylindric protuberance at the medial aspect of the descending or horizontal duodenum at the site of the sphincter of Oddi. It is finding on small bowel follow-though (and endoscopy) and has a relatively long differential. On cross sectional imaging, the unde...
Article

Burkitt lymphoma

Burkitt lymphoma (BL) is an aggressive B-cell lymphoma that predominantly affects children. Epidemiology Burkitt lymphoma is the most common (40%) type of non-Hodgkin lymphoma in childhood. The median age of Burkitt lymphoma is eight years, and it has a male predominance (M:F = 4:1) 1. It is l...
Article

CA 19-9 elevation

CA 19-9 is a serum antigen (monosialoganglioside) that has increased diagnostic use in the management of several malignancies, mainly of hepato-pancreatico-biliary origin. It is nonspecific, however, and can rise in both malignant and nonmalignant conditions. Elevation of serum CA 19-9 has been...
Article

CA-125

Serum CA-125 is well recognised as an ovarian cancer-associated marker and is an antigen determinant on a high-molecular-weight glycoprotein. The normal range of CA-125 is 0-35 U/mL. Serum CA-125 levels can also be used to monitor the response to treatment as well as a prognostic indicator sinc...
Article

Calcified mediastinal lymph nodes (differential)

There are numerous causes of calcified mediastinal lymph nodes. Common causes include: infectious granulomatous diseases tuberculosis histoplasmosis sarcoidosis silicosis treated lymphoma Uncommon causes include: Pneumocystis jiroveci (PCP) pneumonia metastases thyroid carcinoma: papi...
Article

Cancer staging list

Cancer staging using a number of systems to help direct treatment and aid prognosis.  Staging systems TNM FIGO (in gynaecological cancer) Dukes staging system Examples Breast breast cancer staging Chest non-small cell lung cancer staging small cell lung cancer staging malignant pleura...
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Cannonball metastases (lungs)

Cannonball metastases refer to large, well circumscribed, round pulmonary metastases that appear, well, like cannonballs. The French term "envolée de ballons" which translates to "balloons release" is also used to describe this same appearance. Metastases with such an appearance are classically...
Article

Carcinoembryonic antigen

Serum carcinoembryonic antigen (CEA) is a cell-adhesive glycoprotein that was discovered in colorectal cancer in 1965, and is hence one of the oldest and most used tumour markers. Its name derives from its normal expression in fetoembryonic liver, gut and pancreas tissue. Normal range of CEA is...
Article

Carcinoid cardiac lesions

Carcinoid cardiac lesions are a known complication of carcinoid tumours and are particularly prevalent in those who develop the carcinoid syndrome (up to 50%). Pathology There is thickening of the mural and valvular endothelial surfaces of right-sided cardiac structures. This is thought to occ...
Article

Carcinoma of the cervix

Carcinoma of the cervix is a malignancy arising from the cervix and is considered the third most common gynaecologic malignancy (after endometrial and ovarian). Epidemiology It typically presents in younger women with the average age of onset at around 45 years.  Risk factors human papilloma...
Article

Carcinosarcoma

Carcinosarcomas are highly malignant biphasic tumours with both carcinomatous (epithelial) and sarcomatous (bone, cartilage, or skeletal muscle) components.  Pathology It can arise in many organs: lung 5: pulmonary carcinosarcoma oesophagus 1: oesophageal carcinosarcoma genitourinary tract ...
Article

Cardiac myxoma

Cardiac myxomas, although uncommon are one of commonest primary cardiac tumours and account for ~50% primary benign cardiac tumours.  Epidemiology Cardiac myxomas are the most common primary cardiac tumour in adults but are relatively infrequent in childhood, where cardiac rhabdomyomas are mor...
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Cardiophrenic angle lesions

The cardiophrenic space is usually filled with fat. However, lesions originating above or lower to the diaphragm can present as cardiophrenic angle lesions. The more common lesions encountered include: pericardial fat pad pericardial cyst pericardial fat necrosis Morgagni's hernia lymphade...
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Causes of perfusion defects on a VQ scan

There are several causes leading to a perfusion defect on a VQ scan with an acute pulmonary embolus being only one of them: Vascular causes acute pulmonary embolus previous pulmonary embolus (including fat embolism, thromboembolism, air embolism, tumour) vasculitides affecting the pulmonary ...
Article

Central neurocytoma

Central neurocytomas are WHO grade II neuroepithelial intraventricular tumours with fairly characteristic imaging features, appearing as heterogeneous masses of variable size and enhancement within the lateral ventricle, typically attached to the septum pellucidum. They are typically seen in you...
Article

Cerebral radiation necrosis

Cerebral radiation necrosis refers to necrotic degradation of brain tissue following intracranial or regional radiation either delivered for the treatment of intracranial pathology (e.g. astrocytoma, cerebral arteriovenous malformation) or as a result of irradiation of head and neck tumours (e.g...
Article

Cerebral ring enhancing lesions

The differential for peripheral or ring enhancing cerebral lesions includes: cerebral abscess tuberculoma neurocysticercosis metastasis glioblastoma subacute infarct /haemorrhage /contusion demyelination (incomplete ring) tumefactive demyelinating lesion (incomplete ring) radiation necr...
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Cerebral ring enhancing lesions (mnemonic)

Convenient mnemonics for the causes of cerebral ring enhancing lesions are: MAGIC DR or DR MAGIC DR MAGIC L MAGICAL DR Mnemonics MAGIC DR or DR MAGIC M: metastasis A: abscess G: glioblastoma I: infarct (subacute phase) C: contusion D: demyelinating disease R: radiation necrosis or re...
Article

Cervical lymph node (staging)

Cervical lymph node staging is important in a variety of tumours, especially squamous cell carcinoma of the head and neck. TNM nodal staging Nodal staging is the same for squamous cell carcinomas of most regions of the upper aerodigestive tract of the head and neck, including those of the of t...
Article

Chemotherapy induced cholangitis

Chemotherapy induced cholangitis is caused when intra-arterial chemotherapy is introduced to treat liver metastases. This causes strictures of the common hepatic duct and main ducts, but spares distal and proximal (i.e. common bile duct and intrahepatic ducts).  Radiographic features similar t...
Article

Childhood malignancies

Unfortunately the paediatric population is susceptible to malignancies. The most common entities, in overall order of frequency, are 1-4: leukaemia/lymphoma: ~35% * acute lymphoblastic leukaemia: 23% Hodgkin disease: 5% acute myelogenous leukaemia: 4% central nervous system malignancies: ~2...
Article

Cholangiohepatoma

Cholangiohepatoma refers to a synchronous cholangiocarcinoma and hepatocellular carcinoma. It is a rare and aggressive primary hepatic tumour. The origin of cholangiohepatoma is closely linked to the origin of cholangiocarcinoma rather than hepatocellular carcinoma (HCC). Epidemiology The inci...
Article

Choledochal cyst

Choledochal cysts represent congenital cystic dilatations of the biliary tree. Diagnosis relies on the exclusion of other conditions (e.g. tumour, gallstone, inflammation) as a cause of biliary duct dilatation. Epidemiology Choledochal cysts are rare, with an incidence of 1:100,000-150,000. Al...
Article

Choriocarcinoma

Choriocarcinoma is an aggressive, highly vascular tumour. When it is associated with gestation, it is often considered part of the spectrum of gestational trophoblastic disease; it is then termed gestational choriocarcinoma. When it occurs in the absence of preceding gestation, it is termed non-...
Article

Circumferential resection margin

The circumferential resection margin (CRM) is a term used in rectal carcinoma excision surgery (such as total mesorectal excision (TME). Pathologic evaluation of the resection margin on the excised rectum has been considered important for determining the risk of local recurrence. A margin of ≤1...
Article

CNS capillary telangiectasia

CNS capillary telangiectasiae(s) are small, asymptomatic low flow vascular lesions of the brain.  Epidemiology As these lesions are asymptomatic, diagnosis usually matches the age of first imaging with MRI, and as such are most frequently found in middle-aged and elderly adults. Their incidenc...
Article

Coarsened hepatic echotexture

Coarsened hepatic echotexture is a sonographic descriptor where there uniform smooth hepatic echotexture of the liver is lost. This can occur due to number of reasons which include: conditions that cause hepatic fibrosis 1 cirrhosis haemochromatosis various types of hepatitis 3 particularly...
Article

Colorectal cancer (summary)

Colorectal cancer, also called colorectal carcinoma (CRC), is the most common cancer of the gastrointestinal tract and the second most frequently diagnosed malignancy in adults. CT and MRI are the modalities most frequently used for staging. Surgical resection may be curative although five-year ...
Article

Colorectal carcinoma

Colorectal carcinoma (CRC) is the most common cancer of the gastrointestinal tract and the second most frequently diagnosed malignancy in adults. CT and MRI are the modalities most frequently used for staging. Surgical resection may be curative although five-year survival rate is 40-50%. Epidem...
Article

Congenital heart disease chest x-ray (an approach)

With the advent of echocardiography, and cardiac CT and MRI, the role of chest radiographs in evaluating congenital heart disease has been largely been relegated to one of historical and academic interest, although they continue to crop up in radiology exams. In most instances a definite diagnos...
Article

Congenital neuroblastoma

A congenital neuroblastoma is defined as neuroblastoma identified within a month of birth, and is divided into : fetal neuroblastoma neonatal neuroblastoma In most cases they present as stage 1, 2 or 4S (see neuroblastoma staging). Fetal neuroblastoma In 90% of cases fetal neuroblastomas ar...
Article

Cortically-based brain tumours (mnemonic)

A handy mnemonic to recall cortically-based brain tumours is: PDOG Mnemonic P: pleomorphic xanthoastrocytoma D: dysembryoplastic neuroepithelial tumour (DNET); desmoplastic infantile astrocytoma and ganglioglioma O: oligodendroglioma G: ganglioglioma
Article

CT angiogram sign (lungs)

The CT angiogram sign refers to vessels appearing prominent during a contrast enhanced CT as they traverse an airless low attenuation portion of consolidated lung. Although initially thought to be specific for bronchoalveolar carcinoma, it has now been recognised as a generic appearance provided...
Article

CT guided thoracic biopsy

CT guided thoracic biopsy is usually performed for the diagnosis of suspicious lung, pleural or mediastinal lesions. It can be performed as an outpatient where patient monitoring and complications support are available. Indications pulmonary lesion inaccessible to bronchoscopy, or in which pri...
Article

Curtain sign

The curtain sign (or draped curtain sign) in neuroimaging refers to the appearance of a vertebral body mass that extends to the anterior epidural space. The posterior longitudinal ligament is strongly attached to the posterior vertebral body cortex in the midline and is more loosely attached la...
Article

Cutaneous and subcutaneous metastases

Cutaneous and subcutaneous metastases are uncommon, occurring in ~5% (range 0.7-10%) of internal malignancies. Sister Mary Joseph nodule is a well known cutaneous metastases. Pathology These metastases can come from haematogenous or lymphatic spread, or may result from seeding from a surgical ...
Article

Cystic (necrotic) lymph nodes

Cystic or necrotic appearing lymph nodes can be caused by a number of infectious, inflammatory or malignant conditions: Systemic squamous cell carcinoma metastases treated lymphoma leukemia plasmacytoid T-cell leukemia acute myeloid leukemia viral lymphadenitis herpes simplex lymphadenit...
Article

Cystic adrenal neoplasm

Cystic adrenal neoplasms are uncommon and only account for a minority of cystic adrenal lesions 3. They may be represented several histological types: adrenal adenoma 1 adrenal cortical carcinoma 1,2 adrenal epithelioid angiosarcoma 2 phaeochromocytoma 1 Differential diagnosis Consider adr...

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