Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and edited by countless contributing members over a period of time. A global group of dedicated editors oversee accuracy, consulting with expert advisers, and constantly reviewing additions.

494 results found
Article

Choroid plexus malignancy

Choroid plexus malignancies can be classified as primary or secondary neoplasms of the choroid plexus: primary choroid plexus papilloma (CPP) 80% WHO Grade I, and WHO Grade II when atypical choroid plexus carcinoma (CPC)  20% WHO Grade III intraventricular meningioma secondary choroid ...
Article

Circumferential resection margin

The circumferential resection margin (CRM) is a term used in rectal carcinoma excision surgery (such as total mesorectal excision (TME)). Pathologic evaluation of the resection margin on the excised rectum has been considered important for determining the risk of local recurrence. A margin of ≤...
Article

Clavicle tumours

Clavicle tumours may be malignant or benign. Malignant metastases prostate breast cervix ovary urinary bladder carcinoid osteosarcoma osteosarcoma lymphoma primary metastatic Benign osteoma: uncommon, sclerotic, hamartomatous surface lesion enchondroma: rare, geographic, intramed...
Article

Clear cell meningioma

Clear cell meningiomas are a histological variant of meningioma with poorer prognosis and a higher rate of recurrence. They are therefore considered WHO grade 2 tumours, regardless of mitotic index, cellular atypia/anaplasia, or presence of brain invasion.  Epidemiology Clear cell meningiomas ...
Article

Clear cell sarcoma of the kidney

Clear cell sarcomas of the kidney (CCSK) are a rare mesenchymal renal tumour that account for ~5% of primary renal neoplasms in the paediatric population 1.  Epidemiology Clear cell sarcoma of the kidney is the second most common primary malignant paediatric renal neoplasm after Wilms tumour, ...
Article

Clear cell tumour of the lung

Clear cell tumours of the lung are rare benign pulmonary neoplasms that contain an abundant amount of glycogen. It is often classified under the spectrum of perivascular epithelioid cell tumours (PEComas). Radiographic features Usually seen as a rounded, smooth-walled, and peripheral parenchym...
Article

CNS capillary telangiectasia

CNS capillary telangiectasiae(s) are small, asymptomatic low flow vascular lesions of the brain.  Epidemiology As these lesions are asymptomatic, diagnosis usually matches the age of first imaging with MRI, and as such are most frequently found in middle-aged and elderly adults. Their inciden...
Article

Coarsened hepatic echotexture

Coarsened hepatic echotexture is a sonographic descriptor where there uniform smooth hepatic echotexture of the liver is lost. This can occur due to number of reasons which include: conditions that cause hepatic fibrosis 1 cirrhosis haemochromatosis various types of hepatitis 3 particularly...
Article

Coeliac plexus block

Coeliac plexus block under image guidance is an easy and safe percutaneous procedure with good outcomes for pain palliation in patients who have chronic abdominal pain related to the coeliac ganglia.  This usually includes patients with advanced cancers, especially from upper abdominal viscera,...
Article

Colon polyp

Colon polyps are mucosal outgrowths of the colon wall. They are of interest to physicians and radiologists because of the accepted progression of adenomatous polyps to colon carcinoma. Pathology adenomatous colon polyps tubular polyps tubulovillous polyps villous colon polyps dysplastic co...
Article

Colorectal cancer (summary)

This is a basic article for medical students and other non-radiologists Colorectal cancer, also called colorectal carcinoma (CRC), is the most common cancer of the gastrointestinal tract and the second most frequently diagnosed malignancy in adults. CT and MRI are the modalities most frequently...
Article

Colorectal carcinoma

Colorectal carcinoma (CRC) is the most common cancer of the gastrointestinal tract and the second most frequently diagnosed malignancy in adults. CT and MRI are the modalities most frequently used for staging. Surgical resection may be curative although five-year survival rate is 40-50%. Epidem...
Article

Computed tomography texture analysis

Computed tomography texture analysis (or CTTA) is a new useful biomarker that provides an objective and quantitative assessment of tumour heterogeneity by analysing the differences in the pixel values of an image. Parameters assessed  Gray-level frequency distribution: pixel intensity histogra...
Article

Congenital heart disease chest x-ray (an approach)

With the advent of echocardiography, and cardiac CT and MRI, the role of chest x-rays in evaluating congenital heart disease has been largely been relegated to one of historical and academic interest, although they continue to crop up in radiology exams. In most instances a definite diagnosis ca...
Article

Congenital neuroblastoma

A congenital neuroblastoma is defined as neuroblastoma identified within a month of birth, and is divided into : fetal neuroblastoma neonatal neuroblastoma In most cases they present as stage 1, 2 or 4S (see neuroblastoma staging). Fetal neuroblastoma In 90% of cases fetal neuroblastomas ar...
Article

Cortically-based brain tumours (mnemonic)

A handy mnemonic to recall cortically-based brain tumours is: PDOG Mnemonic P: pleomorphic xanthoastrocytoma D: dysembryoplastic neuroepithelial tumour (DNET); desmoplastic infantile astrocytoma and ganglioglioma O: oligodendroglioma G: ganglioglioma
Article

CT angiogram sign (lungs)

The CT angiogram sign refers to vessels appearing prominent during a contrast enhanced CT as they traverse an airless low attenuation portion of consolidated lung. Although initially thought to be specific for bronchoalveolar carcinoma, it has now been recognised as a generic appearance provided...
Article

CT guided thoracic biopsy

CT guided thoracic biopsy is usually performed for the diagnosis of suspicious lung, pleural or mediastinal lesions. It can be performed as an outpatient where patient monitoring and complications support are available.  A small percentage of lung and pleural biopsies may be performed under ultr...
Article

Curtain sign

The curtain sign (or draped curtain sign) in neuroimaging refers to the appearance of a vertebral body mass that extends to the anterior epidural space. The posterior longitudinal ligament is strongly attached to the posterior vertebral body cortex in the midline and is more loosely attached la...
Article

Cutaneous and subcutaneous metastases

Cutaneous and subcutaneous metastases are not uncommon, occurring in ~5% (range 0.7-10.4%) of internal malignancies, and representing 2% of skin cancers. Sister Mary Joseph nodule is a well known cutaneous metastases. Pathology These metastases can come from haematogenous or lymphatic spread, ...
Article

Cystic adrenal neoplasm

Cystic adrenal neoplasms are uncommon and only account for a minority of cystic adrenal lesions 3. They may be represented several histological types: adrenal adenoma 1 adrenal cortical carcinoma 1,2 adrenal epithelioid angiosarcoma 2 phaeochromocytoma 1 Differential diagnosis Consider adr...
Article

Cystic glioblastoma

Cystic glioblastoma is a descriptive term for one form of glioblastoma that contains a large cystic component, rather than being a pathological subtype.  Please refer to the main article on glioblastoma for a broad discussion on this tumour.  Radiographic features The main challenge in discri...
Article

Cystic lesions of the pancreas (differential)

The differential for cystic lesions of the pancreas includes: unilocular pancreatic pseudocyst intraductal papillary mucinous neoplasm (IPMN) serous cystadenoma uncommonly uni/macrolocular simple pancreatic cyst pancreatic cysts occur in association with  von Hippel Lindau syndrome autos...
Article

Cystic meningioma

The term cystic meningioma is applied to both meningiomas with intratumoral degenerative cyst formation as well as those with peritumoral arachnoid cysts or reactive intraparenchymal cysts.  They should not be confused with microcystic meningiomas, a distinct variant, in which the cysts are mic...
Article

Cystic (necrotic) lymph nodes

Cystic or necrotic appearing lymph nodes can be caused by a number of infectious, inflammatory or malignant conditions: Systemic squamous cell carcinoma metastases treated lymphoma leukemia plasmacytoid T-cell leukemia acute myeloid leukemia viral lymphadenitis herpes simplex lymphadenit...
Article

Cystic pulmonary metastases

Cystic pulmonary metastases are atypical morphological form on pulmonary metastases where lesions manifest as distinct cystic lesions. It is slightly different form the term cavitating pulmonary metastases in that the lesions are extremely thin walled. Pathology It has been reported with many ...
Article

Deauville five-point scale

The Deauville five-point scale (Deauville 5ps) is an internationally-recommended scale for routine clinical reporting and clinical trials using FDG-PET/CT in the initial staging and assessment of treatment response in Hodgkin lymphoma (HL) and certain types of non-Hodgkin lymphomas (NHL).  Incl...
Article

Deep inguinal lymph nodes

The deep inguinal nodes are located within the femoral sheath, medial to the femoral vein. They receive afferent lymphatic drainage from the deep lymphatics of the distal lower extremity and perineum (e.g. glans penis / clitoris), and drain proximally into external iliac lymph nodes via channels...
Article

Dense hilum sign

The dense hilum sign suggests a pathological process at the hilum or in the lung anterior or posterior to the hilum. Malignancy, especially lung cancer, should be suspected. Radiographic features On a well-centred chest posteroanterior (PA) radiograph the density of the hilum is comparable on ...
Article

Dermatofibrosarcoma protuberans

Dermatofibrosarcoma protuberans (DFSP) is an uncommon exophytic, slow growing, low grade, spindle cell tumour arising in the dermal and subcutaneous tissues, particularly of the trunk region with excellent outcome after complete surgical resection. Epidemiology The tumour occurs in patients of...
Article

Dermatomyositis

Dermatomyositis is an autoimmune inflammatory myositis. Epidemiology There is a recognised female predilection. It has a bimodal age of presentation depending on the variant: juvenile dermatomyositis (JDM): affects children and tends to be more severe adult dermatomyositis (ADM): typically a...
Article

Desmoid tumour

Desmoid tumours are benign, non-inflammatory fibroblastic tumours (see WHO 2002 classification of soft tissue tumours) with a tendency for local invasion and recurrence but without metastasis. Terminology The terms desmoid tumour and aggressive fibromatosis are occasionally used synonymously b...
Article

Desmoplastic fibroma

Desmoplastic fibromas are extremely rare bone tumours that do not metastasise but may be locally aggressive. They are considered to be a bony counterpart of soft tissue desmoid tumours and are histologically identical.  Clinical presentation Incidence is ~0.3%. The most common areas of involve...
Article

Desmoplastic small round cell tumour

Desmoplastic small round cell tumours are a rare and highly aggressive primary peritoneal malignancy. Epidemiology They are usually seen in young adolescents and has male predominance with a mean survival of 2-3 years. Clinical presentation It usually presents with a palpable abdominal mass ...
Article

Diabetic mastopathy

Diabetic mastopathy is a condition characterised by the presence of a benign tumour like breast masses in women with long-standing type 1 or type 2 insulin-dependent diabetes. The condition has also been reported in men. A similar condition is lymphocytic mastitis but this occurs in non-diabetic...
Article

Differential diagnosis for a focal gas collection in the right upper quadrant

A gas filled focal collection in the right upper upper quadrant on plain film can occur from a number of pathologies. Things to consider are entero biliary fistula : common types include cholecysto-duodenal fistula and cholecysto-colic fistula and. Can occur with  gallstone ileus (majority of ...
Article

Differential for an anterosuperior mediastinal mass

An anterosuperior mediastinal mass can be caused by neoplastic and non-neoplastic pathology. As their name suggests, they are confined to the anterior mediastinum, that portion of the mediastinum anterior to the pericardium and below the level of the clavicles.  The differential diagnosis for a...
Article

Diffuse astrocytoma

Diffuse astrocytomas, also referred to as low-grade infiltrative astrocytomas, are designated as WHO II tumours of the brain. The term diffuse infiltrating means there is no identifiable border between the tumour and normal brain tissue, even though the borders may appear well-marginated on imag...
Article

Diffuse bony sclerosis (mnemonic)

Useful mnemonics for remembering causes of diffuse bony sclerosis include: 3 M's PROOF Regular Sex Makes Occasional Perversions Much More Pleasurable And Fantastic 1   Mnemonics 3 M's PROOF M: malignancy metastases (osteoblastic metastases) lymphoma leukaemia M: myelofibrosis M: mastoc...
Article

Diffuse brainstem gliomas

Diffuse brainstem gliomas, also known as diffuse intrinsic brainstem glioma (DIBG), is a term used to describe infiltrating astrocytomas, no longer recognised as a distinct entity in the 2016 update to the WHO classification of CNS tumours. It encompassed a variety of tumours, ranging from WHO g...
Article

Diffusely increased bone marrow FDG uptake

A diffuse homogeneous bone marrow FDG uptake usually reflects hyperplastic bone marrow which can be seen in the following conditions: therapy-related granulocyte colony stimulating factor (G-CSF) post-chemotherapy erythropoietin pathological process myelodysplastic syndromes beta thalasse...
Article

Distal appendicular skeletal metastases

Distal appendicular skeletal metastases, especially distal to the knee and elbow joints, are uncommon. Clinical presentation Localised pain and swelling, along with pathological fractures, are the most common 3.  Pathology Aetiology Malignancies that most commonly spread to appendicular ske...
Article

Ductal adenoma of the breast

A ductal adenoma of the breast is a benign glandular tumour of the breast that usually fills and distends the ductal lumen. Epidemiology They may occur in women of all ages, although the majority of patients are 60 years of age or greater 3. Clinical presentation Ductal adenomas usually pres...
Article

Duodenal filling defects

Duodenal filling defects may be caused by a wide variety of duodenal pathology which may be divided by their location and pathological process. Extrinsic gallbladder impression common bile duct impression gas-filled diverticulum Intrinsic Note: please refer to duodenal mucosal nodular fill...
Article

Dural metastases

Dural or pachymeningeal metastases are a relatively common cause of dural masses, although they are less common than brain metastases and meningiomas. They can occur both within the spine and intracranially - this article is focussed on intracranial dural masses.  Clinical presentation Patient...
Article

Dysembryoplastic neuroepithelial tumour

Dysembryoplastic neuroepithelial tumours (DNET) are benign (WHO Grade I) slow growing glioneuronal tumours arising from either cortical or deep grey matter. The vast majority are centred in cortical grey matter, arise from secondary germinal layers, and are frequently associated with cortical dy...
Article

Dysplastic liver nodules

Dysplastic liver nodules are focal nodular regions (≥ 1 mm) without definite evidence of malignancy. Epidemiology They have been found in cirrhotic patients with a prevalence of 14% (size >1.0 cm) to 37% (size >0.5 cm) 2. Pathology Dysplasia indicates: nuclear atypia increased fat or glyco...
Article

ECOG performance status

The Eastern Cooperative Oncology Group (ECOG) is one of the largest clinical cancer research organizations in the United States and conducts clinical trials in all types of adult cancers. The ECOG performance status is a scale used to assess how a patient's disease is progressing, assess how th...
Article

Endometrial carcinoma

Endometrial carcinoma is generally considered the most common gynaecological malignancy 1,5. It frequently presents with vaginal bleeding. Both ultrasound and pelvic MRI are useful modalities for evaluation. Epidemiology Endometrial carcinoma is the most common gynaecological malignancy, with ...
Article

Endometrial hyperplasia

Endometrial hyperplasia is abnormal proliferation of the endometrial glands and stroma, defined as diffuse smooth thickening >10 mm 13. One of the main concerns is the potential malignant transformation of the endometrial hyperplasia to endometrial carcinoma. Epidemiology Endometrial hyperplas...
Article

Endosteal scalloping

Endosteal scalloping refers to the focal resorption of the inner layer of the cortex (i.e. the endosteum) of bones, most typically long bones, due to slow-growing medullary lesions. It is important to note that although it is evidence of a slow non-infiltrative lesion, it does not equate to ben...
Article

Eosinophil

Eosinophils (or less commonly acidophiles) are myeloid granulocytes and form one of the main types of white blood cells. Their counts are routinely measured as part of a full blood count. They have important roles in fighting parasitic infections, but it is increasingly recognised that they have...
Article

Ependymoma

Ependymomas represent a relatively broad group of glial tumours most often arising from the lining the ventricles of the brain or the central canal of the spinal cord. They account for ~5% of all neuroepithelial neoplasms, ~10% of all paediatric brain tumours and up to 33% of brain tumours occur...
Article

Exophytic (definition)

Exophytic is a descriptive term used by radiologists/pathologists to describe solid organ lesions arising from the outer surface of the organ of origin. Literally exophytic only refers to those lesions arising from the outer surface, however radiologists and pathologists use the term to include...
Article

Extramedullary haematopoiesis

Extramedullary haematopoiesis is a response to the failure of erythropoiesis in the bone marrow. This article aims to a general approach on the condition, for a dedicated discussion for a particularly involved organ, please refer to the specific articles on:  extramedullary haematopoiesis in t...
Article

Extramedullary haematopoiesis in the spleen

Extramedullary haematopoiesis in the spleen represents a physiologic compensatory event that may be seen in many haematologic diseases leading to chronic anaemia. The liver and the spleen are the most common site of extramedullary haematopoiesis, both usually manifesting on imaging as organomega...
Article

Facial nerve schwannoma

Facial nerve schwannoma (FNS), also known as facial nerve neuroma/neurilemoma, is a schwannoma that arises from the facial nerve. They are generally uncommon, and when involving the temporal bone, make up less than 1% of all temporal bone tumours. Epidemiology FNS is a rare tumour 2. Clinical...
Article

Fascicular sign

Fascicular sign is a finding on T2-weighted MRI images that suggests a lesion of neurogenic origin. It is characterised by multiple small ring-like structures with peripheral hyperintensity representing the fascicular bundles within the nerves. It is found in various neurogenic tumours, includi...
Article

Fetal cardiac tumours

Fetal cardiac tumours refer to primary cardiac tumours that can present in the in utero population.  Epidemiology Fetal cardiac tumours are rare; the prevalence, reported from autopsy studies of patients of all ages, varies from 0.0017-0.28 % 2. Pathology Known cardiac tumour types that pres...
Article

Fibrinous pericarditis

Fibrinous pericarditis results from fine granular roughening of the pericardium. Clinical presentation Pericardial friction rub may be heard. Pathology Causes viral acute idiopathic tuberculosis pyogenic acute rheumatic fever myocardial infarction: Dressler syndrome chronic renal fail...
Article

Fibrosarcoma of the breast

Fibrosarcoma of the breast is a type of malignant stromal sarcoma that rarely occurs as a primary tumour within the breast.  Pathology A fibrosarcoma is composed of immature mesenchymal elements surrounded by a collagenous substance. It is a type of breast sarcoma with a predominant “herringbo...
Article

FIGO staging system

The FIGO staging systems are determined by the International Federation of Gynecology and Obstetrics (Fédération Internationale de Gynécologie et d’Obstétrique). In general, there are five stages: stage 0: carcinoma in situ (common in cervical, vaginal, and vulval cancer) stage I: confined to...
Article

Flare phenomenon (bone scintigraphy)

Flare phenomenon or osteoblastic flare phenomenon refers to interval visualisation of lesions with a sclerotic rim around an initially lytic lesion or sclerosis of lesions previously undetected on radiograph or CT in the setting of follow-up of an oncological patient with other signs of partial ...
Article

Fluorine-18-labeled sodium fluoride

Fluorine-18-labeled sodium fluoride (also known as 18F-NaF or sodium fluoride) is a PET radiotracer used primarily for skeletal imaging. Structure Fluorine-18-labeled sodium fluoride is an ionic compound comprised of a single sodium atom bound to a positron-emitting isotope of fluorine.  Dist...
Article

Focal fatty sparing of the liver

Focal fatty sparing of the liver is the localised absence of increased intracellular hepatic fat, in a liver otherwise fatty in appearance i.e. diffuse hepatic steatosis. Recognition of this finding is important to prevent the erroneous belief that the region of sparing is itself a mass. Epidem...
Article

Focal sclerotic bony lesions (mnemonic)

A popular mnemonic to help remember causes of focal sclerotic bony lesions is: HOME LIFE Mnemonic H: healed NOF O: osteoma M: metastasis E: Ewing sarcoma L: lymphoma I: infection or infarct F: fibrous dysplasia E: enchondroma
Article

Follicular lymphoma

Follicular lymphoma is the most common subtype of non-Hodgkin lymphoma (NHL) Epidemiology Estimated to account for ~45% of all NHL cases 1. Higher rates in North America and Europe 4.  Pathology Nodal effacement by closely packed follicles containing small cleaved cells without nucleoli (cen...
Article

Follicular thyroid cancer

Follicular thyroid carcinoma (FTC) is the second most frequent malignancy of the thyroid gland after papillary cancer and accounts for ≈10-20% of all thyroid neoplasms.  Epidemiology It typically occurs in women and in an older age group than papillary (i.e. 40-60 years of age). Pathology Un...
Article

Fukuoka consensus guidelines

The Tanaka criteria, also referred to as the Fukuoka consensus guidelines, is a classification system for intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs).  The prior international consensus guidelines (2006) were referred to as the Sendai criteria, which la...
Article

Ga-68 DOTATATE

68Ga-DOTATATE​​ is a PET radiotracer that is useful for evaluating primary and metastatic well-differentiated neuroendocrine tumours.  It is a form of somatostatin-receptor (SSTR) functional imaging and most often combined with cross-sectional imaging in the form of PET/CT. Terminology 68Ga-DO...
Article

Gallbladder carcinoma

Gallbladder carcinomas are usually asymptomatic until they reach an incurable stage. As such, early incidental detection is important, if the occasional patient is to be successfully treated. The majority (90%) are adenocarcinomas, and the remainder is squamous cell carcinomas.  Epidemiology A...
Article

Gallbladder metastases

Gallbladder metastases are rare and usually represent an advanced and end-stage of malignancy. Epidemiology They represent <5% of all gallbladder cancers 1. Clinical presentation Most patients with gallbladder metastases are asymptomatic, and the metastases are detected on surveillance or st...
Article

Gastric adenocarcinoma

Gastric adenocarcinoma, commonly referred to as gastric cancer, refers to a primary malignancy arising from the gastric epithelium. It is the most common gastric malignancy.  Epidemiology Gastric cancer is rare before the age of 40, but its incidence steadily climbs after that and peaks in the...
Article

Gastric cancer (summary)

This is a basic article for medical students and other non-radiologists Gastric cancer, also known as stomach cancer or gastric carcinoma, refers to a cancer that arises from the mucosal lining of the stomach. It is the commonest gastric malignancy. Reference article This is a summary article...
Article

Gastrointestinal stromal tumour

Gastrointestinal stromal tumours (GIST) are the most common mesenchymal tumours of the gastrointestinal tract. They account for ~5% of all sarcomas. They respond remarkably well to chemotherapy.  Terminology Previously these tumours have been variably referred to as leiomyomas, leiomyosarcomas...
Article

Generalised osteopenia

Generalised osteopenia refers to osteopenia diffusely affecting the bones. Differential diagnosis The differential diagnosis is wide and includes includes: osteoporosis: decreased osteoid production osteomalacia: undermineralisation of osteoid hyperparathyroidism multiple myeloma diffuse ...
Article

Germ cell tumours (mnemonic)

A mnemonic for differential diagnosis for germ cell tumours is: SECTE Mnemonic S: seminoma E: embryonal cell carcinoma C: choriocarcinoma T: teratoma E: endodermal sinus tumour (yolk sac tumour)
Article

Giant breast masses

Many patients, particularly in developing countries, can present late with giant breast masses. They may be single or multiple and either benign or malignant. Many of these conditions are indistinguishable on physical examination alone. Some of these lesions require mastectomy while others can b...
Article

Granulocytic sarcoma

Granulocytic sarcoma (also called myeloid sarcoma and chloroma) is a rare neoplasm comprised of myeloid precursor cells. Epidemiology It is typically seen is in children with ~60% occurring in individuals less than 15 years of age. There is no recognised gender predilection. Granulocytic sarc...
Article

Gynaecologic imaging reporting and data system (GI-RADS)

The Gynecologic Imaging Reporting and Data System (GI-RADS) is a reporting system that was created for reporting the findings in adnexal masses based on transvaginal ultrasonography. Classification Findings are classified into five categories 1: GI-RADS 1 normal ovaries identified and no adn...
Article

Haemangioblastoma (central nervous system)

Haemangioblastomas are tumours of vascular origin and occur both sporadically and in patients with von Hippel Lindau (vHL). They are WHO grade I tumours that can occur in the central nervous system or elsewhere in the body, including kidneys, liver, and pancreas. These tumours generally present...
Article

Haemorrhage exclusion sign (prostate)

The haemorrhage exclusion sign can be a useful MRI finding following prostate biopsy. Pathology The normal prostate produces high concentrations of citrate, which among other properties, acts as an anticoagulant 1. As tumour cells are dysfunctional, they will produce lower levels of citrate th...
Article

Haemorrhagic metastases (mnemonic)

A mnemonic for primary malignancies responsible for haemorrhagic metastases is: MR CT BB Mnemonic M: melanoma: metastatic melanoma to brain R: renal cell carcinoma C: choriocarcinoma T: thyroid carcinoma, teratoma B: bronchogenic carcinoma B: breast carcinoma
Article

Hand-foot syndrome (chemotherapy)

Hand-foot syndrome, also known as palmar-plantar erythrodysaesthesia or Burgdorf reaction, is a benign, aseptic, self-limiting complication of many chemotherapeutic agents characterised by a widespread erythema, oedema and ulceration of the hands and feet.  Causative drugs Many chemotherapeuti...
Article

Head and neck cancer therapy response interpretation (Hopkins criteria)

The head and neck cancer therapy response interpretation (Hopkins criteria) is a qualitative system of interpretation for therapy response assessment using PET-CT. Background Widely used options for therapy response assessment are clinical examination, histopathology, CT  and MR imaging, howev...
Article

Head and neck squamous cell carcinomas

Head and neck squamous cell carcinomas (HNSCC) refer to SCCs of the aerodigestive tract of the head and neck rather than cutaneous SCCs. SCC is the most common tumour of the mucosa of the upper aerodigestive tract, and can occur anywhere there is squamous cell mucosa.  Epidemiology, risk factor...
Article

Hepatic carcinosarcoma

Hepatic carcinosarcoma is a very rare tumour that is defined by mixed histological features.  Terminology This tumour has also been referred to as malignant mixed tumour, spindle cell carcinoma, pseudosarcoma or sarcomatoid carcinoma 1,2.  Pathology Hepatic carcinocarcinoma contain a mixture...
Article

Hepatic metastases

Hepatic metastases are 18-40 times more common than primary liver tumours 6. Ultrasound, CT, and MRI are all useful for detection of hepatic metastases and evaluation across multiple post-contrast CT series, or MRI pulse sequences are necessary.  Epidemiology The demographics of patients with ...
Article

Hepatoblastoma (staging)

As expected there are a number of different staging systems for hepatoblastoma. Staging PRETEXT grouping system of paediatric liver tumours not specific to hepatoblastoma; used in all paediatric liver tumours Intergroup staging system specific for hepatoblastoma (see below) Intergroup stag...
Article

Hepatomegaly

Hepatomegaly refers to an increase in size or enlargement of the liver.  Pathology Aetiology Hepatomegaly can result from a vast range of pathology including, but not limited to, the following: malignancy/cellular infiltrate multiple metastases lymphoma(s) leukaemia(s) hepatocellular car...
Article

Hickman catheter

Hickman catheters (or Hickman lines) are a type of tunnelled central venous access device. Indications chemotherapy administration 2 parenteral nutrition 2 long-term parenteral antibiotic administration 2 Complications Insertion arrhythmia (most common) 1 arterial injury kinking pneumo...
Article

High-grade appendiceal mucinous neoplasms

High-grade appendiceal mucinous neoplasms (HAMN) are rare mucinous tumours of the appendix showing high-grade cytologic atypia, cf. low-grade appendiceal mucinous neoplasms (LAMN). The distinction between both LAMN and HAMN is done on histological grounds and these tumours look the same on imagi...
Article

Histiocytic sarcoma

Histiocytic sarcoma is a rare malignant haematopoietic neoplasm that has been reported in association with other haematological malignancies (particularly B and T cell lymphomas). Pathology It comprises of tumour cells derived from the monocyte/macrophage lineage. Location It usually occurs ...

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.