Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and edited by countless contributing members over a period of time. A global group of dedicated editors oversee accuracy, consulting with expert advisers, and constantly reviewing additions.

788 results found
Article

Necrotising enterocolitis

Necrotising enterocolitis (NEC) is the most common gastrointestinal condition in premature neonates, and continues to have significant mortality and morbidity. Epidemiology NEC usually develops 2-3 days following birth, with 90% developing within the first 10 days of life 4. The incidence is i...
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Necrotising enterocolitis (staging)

Necrotising enterocolitis (NEC) can be staged into three groups, helping to guide appropriate treatment. In general, stage I and II are managed medically whereas stage III is managed surgically. stage I clinical signs lethargy, temperature instability, apnoea, bradycardia emesis, abdominal d...
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Neonatal appendicitis

Neonatal appendicitis is rare, presumably in part due to the short funnel shape to the appendix at that age. Symptoms are non-specific and may mimic necrotising enterocolitis. 
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Neonatal bilious vomiting

Neonatal bilious vomiting has a relatively narrow differential - those conditions that cause intestinal obstruction, but do so distal to the ampulla of Vater.  As such, the list includes: malrotation with midgut volvulus duodenal atresia jejunoileal atresia meconium ileus necrotizing entero...
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Neonatal chest radiograph in the exam setting

The neonatal chest radiograph in the exam setting may strike fear into the heart of many radiology registrars, but it need not! There are only a limited number of diagnoses that will be presented on such films and they are often highlighted by the history. Gestation First of all, have a look ...
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Neonatal encephalopathy

Neonatal encephalopathy is a clinical syndrome referring to signs and symptoms of abnormal neurological function in the first few days of life in a neonate born at or beyond 35 weeks of gestation. It is described as difficulty with initiating and maintaining respiration, depression of tone and r...
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Neonatal herpes simplex encephalitis

Neonatal herpes simplex encephalitis is caused by vertical transmission of infection during passage from birth canal with diffuse cerebral involvement within the first month after birth; in contrast to adult herpes simplex encephalitis, it is commonly related to HSV-2.  Epidemiology The incide...
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Neonatal hydronephrosis

Neonatal hydronephrosis is most commonly diagnosed antenatally as fetal pylectasis, and in the majority of cases is due to pelvi-ureteric junction (PUJ) obstruction.   Pathology Aetiology pelvi-ureteric junction (PUJ) obstruction (50% of cases 1,6) vesicoureteric reflux (~20% of cases 5) po...
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Neonatal hypoxic-ischaemic encephalopathy

Neonatal hypoxic-ischaemic encephalopathy (HIE) is the result of a global hypoxic-ischaemic brain injury in a term neonate, usually after asphyxia. Terminology It is important to remember that neonatal encephalopathy may result from a variety of conditions and hypoxic-ischaemic brain injury is...
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Neonatal lines and tubes

Neonatal lines and tubes are widely used in the NICU (neonatal intensive care unit) in the management of critically ill neonates. Examples include: nasogastric tube endotracheal tube central venous line umbilical artery catheter umbilical vein catheter Nasogastric tube The NG tube serves ...
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Neonatal pneumonia

Neonatal pneumonia refers to inflammatory changes of the respiratory system caused by neonatal infection. Epidemiology It is one of the leading causes of significant morbidity and mortality in developing countries. Neonatal pneumonia accounts for 10% of global child mortality. At the time of w...
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Neonatal pneumoperitoneum

The causes of neonatal pneumoperitoneum are different from adult pneumoperitoneum and include: perforated hollow viscus necrotising enterocolitis (NEC): most common meconium ileus in cystic fibrosis Hirschsprung disease intestinal atresia or web peptic ulcer disease iatrogenic intubation...
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Neonatal pneumothorax

Neonatal pneumothorax describes pneumothoraces occurring in neonates. It is a life threatening condition, associated with high morbidity and mortality. The diagnosis is a challenge especially when the amount of air is small and may accumulate along the anterior or medial pleural space. Epidemio...
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Neonatal respiratory distress (causes)

Causes of neonatal distress can be broadly split into intrathoracic, extrathoracic and systemic: Intrathoracic Medical respiratory distress syndrome (RDS) transient tachypnoea of the newborn (TTN) meconium aspiration syndrome bronchopulmonary dysplasia (BPD) patent ductus arteriosus (PDA)...
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Nephroblastomatosis

Nephroblastomatosis refers to diffuse or multifocal involvement of the kidneys with nephrogenic rests (persistent metanephric blastema). Epidemiology Nephrogenic rest are found incidentally in 1% of infants. Pathology Nephrogenic rests are foci of metanephric blastema that persist beyond 36 ...
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Nephrotic syndrome

Nephrotic syndrome (NS) results from loss of plasma proteins in the urine and characterised by hypoalbuminemia, hyperalbuminuria, hyperlipidemia, and oedema. It may be caused by primary (idiopathic) renal disease or by a variety of secondary causes. Clinical presentation Patients present with ...
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Neuhauser sign (distal ileum)

Neuhauser sign refers to a soap bubble appearance seen in the distal ileum in cases of meconium ileus, related to the air mixed with meconium. It may be seen with barium enema if contrast passes beyond the ileocaecal valve or with small-bowel follow-through. Although classically described with ...
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Neurenteric canal of Kovalevsky

The neurenteric canal or canal of Kovalevsky is the transient communication of the amnion through notochordal canal to the yolk sac during notochordal formation at day 16-17. Abnormalities during this stage produce the neurenteric cyst spectrum.
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Neurenteric cyst

Neurenteric cysts are a rare type of foregut duplication cyst, accounting for ~1% of all spinal cord tumours. They are usually classified as spinal or intracranial, and are associated with vertebral or CNS abnormalities respectively.  Pathology Neurenteric cysts result from incomplete resorpti...
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Neuroblastic tumours

Neuroblastic tumours arise from primitive cells of the sympathetic system and include the following entities: neuroblastoma ganglioneuroblastoma ganglioneuroma These entities represent a spectrum of disease from undifferentiated and aggressive (neuroblastoma) to the well differentiated and l...
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Neuroblastoma

Neuroblastomas are tumours of neuroblastic origin corresponding to the most common extracranial solid childhood malignancies and the third commonest childhood tumours after leukaemia and brain malignancies. It accounts for ~15% of childhood cancer deaths. Epidemiology The tumours typically occ...
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Neuroblastoma (staging)

There are two methods of neuroblastoma staging, one that is based on post-operative patients (INSS) and one developed for pre-treatment patients (INRGSS). Staging International Neuroblastoma Staging System (INSS) This staging system is for post-operative patients and mainly for prognosis 1: ...
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Neuroblastoma vs Wilms tumour

Both neuroblastoma and Wilms tumour occur in early childhood and typically present as large abdominal masses closely related to the kidneys. Distinguishing between the two is important, and a number of features are helpful. Neuroblastoma calcification very common: 90% encases vascular structu...
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Neurocristopathy syndromes

Neurocristopathy syndromes encompasses a group of conditions united by abnormal migration, differentiation, division or survival of neural crest cells 1. Examples include: Waardenburg-Shah syndrome Haddad syndrome MEN IIa neurofibromatosis type I (NF1) Sturge-Weber syndrome Bamforth-Lazar...
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Neurofibroma

Neurofibromas are benign peripheral nerve sheath tumours usually solitary and sporadic, however, there is a strong association with neurofibromatosis type 1 (NF1). These tumours present as a well-defined hypodense mass with minimal or no contrast enhancement on CT. On MRI, they usually are T1 hy...
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Niemann-Pick disease

Niemann-Pick disease (NPD) is actually a collection of a number of distinct autosomal recessive lysosomal storage diseases.  deficiency of acid sphingomyelinase 1 Niemann-Pick disease type A (NPA) severe hepatosplenomegaly in infancy severe central nervous system involvement, with atrophy or...
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Niemann-Pick disease (type B)

Niemann-Pick type B disease (NPD-B), along with Niemann-Pick type A (NPD-A) disease, is one of the more common forms of this group of autosomal recessive disorders that share the feature of abnormal storage of sphingomyelin. Common manifestation include splenomegaly and variable neurologic defic...
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Niemann-Pick disease type C

Niemann-Pick disease type c (NPC) is an autosomal recessive lysosomal storage disorder classed under Niemann-Pick disease on account of clinical similarities, namely hepatosplenomegaly and variable involvement of the central nervous system.  Epidemiology NPC is inherited as a autosomal recessi...
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Non-accidental injuries

Non-accidental injuries (NAI) represent both ethical and legal challenges to treating physicians. Radiologists are often the first to suspect NAI when confronted with particular injury patterns, and a knowledge of these is essential if the opportunity to save a child from future neglect is not ...
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Non-decussating retinal-fugal fibre syndrome

Non-decussating retinal-fugal fibre syndrome (NRFFS), also referred to as achiasma, is the isolated congenital absence of optic chiasm with unremarkable rest of the optic pathway and midline structures. Clinically, it typically presents as seesaw nystagmus since childhood. Diagnosis is usually m...
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Non-ossifying fibroma

Non-ossifying fibromas (NOF) are the most common of non-neoplastic fibrous bone lesions and are essentially a larger version (>3 cm) of a fibrous cortical defect; both are encompassed by the term fibroxanthoma or metaphyseal fibrous defect. Epidemiology NOFs are very common in children and ado...
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Noonan syndrome

Noonan syndrome (NS) is a genetically and phenotypically heterogenous non aneuploidic congenital RASopathy. Affected individuals can bear some clinical features similar to that of Turner syndrome.  Epidemiology The estimated incidence is at ~1 in 1000-2500 11. As individuals have normal number...
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Noonan syndrome with multiple lentigines

Noonan syndrome with multiple lentigines, previously known as LEOPARD syndrome (LS), is a rare autosomal dominant RASopathy that has many similarities to Noonan syndrome. Clinical presentation Despite a change in formal name, the 'LEOPARD' acronym is still useful to summarise the clinical feat...
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Normal kidney size in children

The normal size of kidneys in children will naturally depend on the age and size of the child. Based on the children's ages normal average renal length on ultrasound are as follows: 0 to 2 months: 5 cm (approximately 2 inches) 2 months to 6 months: 5.7 cm 6 months to 1 year: 6.2 cm (2.5 inche...
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Normal myelination

After normal myelination in utero, myelination of the neonatal brain is far from complete. The first myelination is seen as early as the 16th week of gestation, in the column of Burdach, but only really takes off from the 24th week 1. It does not reach maturity until 2 years or so. It correlates...
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Normal paediatric imaging examples

This article lists examples of normal imaging of the paediatric patients divided by region, modality, and age. Chest Radiographs chest X-ray premature (27 weeks):  example 1 neonate:  example 1 6-year-old:  example 1 12-year-old: example 1 CT CT chest: examples needed Abdomen Radiogra...
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Norrie disease

Norrie disease is a rare X-linked inherited cause of congenital bilateral blindness. It can present with a retinal mass (pseudoglioma) and cataracts. It is associated with developmental delay and hearing loss. 
Article

Nuchal fold thickness

Nuchal fold thickness is a parameter that is measured in a second-trimester scan (at ~18-22 weeks) and should not be confused with nuchal translucency (which is measured in the first trimester). Pathology The proposed aetiology of increased nuchal thickness is the result of congenital heart di...
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Occipital horn syndrome

Occipital horn syndrome is a rare X-linked disorder of copper metabolism resulting in connective tissue abnormalities. The Menkes kinky hair syndrome is the severe form of this disease, with patients rarely surviving past 3 years of age. Occipital horn syndrome (also known as  X-linked cutis lax...
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Octreoscan

An octreoscan is a scinitigraphic study that uses 111In labelled octreotide which is a somatostatin analog. It is particularly useful for assessment of neuroendocrine tumours. Examples include: carcinoid tumour paraganglioma(s) glomus jugulare tumour glomus jugulotympanicum glomus vagale ...
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Odontohypophosphatasia

Odontohypophosphatasia is the mildest form of hypophosphatasia that manifests as tooth dysplasia and/or early loss of deciduous or permanent teeth. Pathology As with all forms of hypophosphatasia, the underlying abnormality is a mutation in the ALPL gene that encodes for tissue non-specific al...
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Oesophageal atresia

An oesophageal atresia refers to an absence in contiguity of the oesophagus due to an inappropriate division of the primitive foregut into the trachea and oesophagus. This is the most common congenital anomaly of the oesophagus.  Epidemiology It is thought to occur in ~1:3000-4500 live births ...
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Oesophageal atresia (classification)

Oesophageal atresia is closely related to tracheo-oesophageal fistula and can be divided into1: type A: isolated oesophageal atresia (8%) type B: proximal fistula with distal atresia (1%) type C: proximal atresia with distal fistula (85%) type D: double fistula with intervening atresia (1%) ...
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Oesophageal duplication cyst

Oesophageal duplication cysts are a type of congenital foregut duplication cyst. Epidemiology Less common compared to other foregut duplication cysts. There may be an increased male predilection 5. Clinical presentation Patients are generally asymptomatic but may complain of dysphagia due to...
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Omega sign (disambiguation)

The omega sign can refer to a number of different anatomical structures or signs: omega sign (epiglottitis) omega sign (hand bump on the precentral gyrus)
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Omega sign of epiglottitis

The omega sign refers to the thickened aryepiglottic folds and epiglottis seen in epiglottitis, when the larynx is seen endoscopically or via laryngoscope, and not to the appearance on lateral plain films. CT would show the finding, but placing a child with epiglottitis supine to CT their neck i...
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Omphalocoele

Omphalocoeles, or exomphalos, are congenital midline abdominal wall defects at the base of the umbilical cord insertion with herniation of gut (or occasionally other content) out of the fetal abdomen. Epidemiology The estimated occurrence can be up to 1:4000 of live births 3.  Pathology It i...
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Opsomyoclonus

Opsomyoclonus (dancing eyes-dancing feet syndrome) is a clinical syndrome which has a strong association with neuroblastoma. Clinical presentation The “opso-“ refers to the presence of intermittent jerky eye movements (dancing eyes) and the “myoclonus” to myoclonic jerks and cerebellar ataxia ...
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Optic pathway glioma

Optic pathway gliomas are relatively uncommon tumours, with a variable clinical course and usually seen in the setting of neurofibromatosis type I (NF1). Histologically the majority are pilocytic astrocytomas.  They are characterised on imaging by an enlarged optic nerve seen either on CT or MR...
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Orthoroentgenogram

Orthoroentgenogram is a radiographic study used to evaluate anatomic leg length and calculate leg-length discrepancies. This study utilises a long ruler placed on the film, and three radiographs including bilateral hips, knees and ankles. Similar studies used to evaluate true leg length include...
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Osgood-Schlatter disease

Osgood-Schlatter disease (OSD) is a chronic fatigue injury due to repeated microtrauma at the patellar ligament insertion onto the tibial tuberosity, usually affecting boys between 10-15 years. Epidemiology Osgood-Schlatter disease is seen in active adolescents, especially those who jump and k...
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Ossification centres of the elbow

There are six ossification centres of the elbow that appear and develop in a relatively reproducible fashion, and are key to assessment of the paediatric elbow radiograph. Timing of their appearance varies in the literature but an approximation is given below. A useful mnemonic to remember the o...
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Ossification centres of the foot

Primary ossification centres present at birth Visible on x-ray from birth: calcaneus: 6 months in utero talus: 7 months in utero cuboid: 9 months in utero metatarsals: 9 weeks in utero phalanxes: 3-10 months (proximal to distal) Primary ossification centres developing after birth Become ...
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Ossifying renal tumour of infancy

Ossifying renal tumour of infancy (ORTI) is a rare renal tumour. Epidemiology extremely rare, <<1% of paediatric renal neoplasms (17 cases reported) 6 days - 3 months male predominant Pathology Histology reveals spindle cells and osteoblastic cells in a calcified osteoid matrix. It is thou...
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Osteofibrous Dysplasia

Osteofibrous dysplasia is a benign fibro-osseous cortical lesion that almost exclusively occurs in the tibia and fibula. It is most commonly seen in the mid-diaphysis of the tibia. Some consider it synonymous with ossifying fibroma because of histological similarities, but it is generally consid...
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Osteogenesis imperfecta

Osteogenesis imperfecta (OI) refers to a heterogeneous group of congenital, non-sex-linked, genetic disorders of collagen type I production, involving connective tissues and bones.  The hallmark feature of osteogenesis imperfecta is osteoporosis and fragile bones that fracture easily, as well a...
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Osteogenesis imperfecta classification

The several forms of osteogenesis imperfecta (OI) have been classified, representing wide variation in appearance and severity, and clinical features vary widely not only between types but within types. Classification OI was initially classified by type according to a scheme developed by Dr Da...
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Osteoid osteoma

Osteoid osteomas are benign bone forming tumours that typically occur in children (particularly adolescents). They have characteristic lucent nidus <2 cm and surrounding solid periosteal reaction and classically cause night pain that is relieved by the use of salicylate analgesia, e.g. aspirin. ...
Article

Osteopetrosis

Osteopetrosis, or Albers-Schönberg disease, is an uncommon hereditary disorder that results from defective osteoclasts. Bones become sclerotic and thick, but their abnormal structure results in them being both weak and brittle. There are two separate subtypes of osteopetrosis: infantile autoso...
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Oxycephaly

Oxycephaly (also known as turricephaly) is the most severe of the craniosynostoses and results from the premature closure of all sutures. Characterised by a tower-like skull which may be associated with: 8th cranial nerve lesion optic nerve compression mental deficiency syndactyly
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Paediatric cardiovascular procedures

A number of paediatric cardiovascular procedures are encountered when reporting paediatric imaging. They include: Blalock-Taussig (BT) shunt classic: end to side subclavian to ipsilateral pulmonary arterial anastomosis modified: graft anastomosis Waterston shunt Sano shunt: right ventricle ...
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Paediatric cervical lesions (differential)

The differential diagnosis of paediatric cervical lesions is commonly encountered in practice, unfortunately, the list is long.  Differential diagnosis Inflammatory Most lesions tend to be inflammatory 3: nontuberculous lymphadenitis scrofula sialodochitis abscess infected branchial cle...
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Paediatric clavicle abnormalities

The clavicle is a unique bone and as such it often displays unique pathology. The following is an attempt to summarise paediatric clavicle abnormalities. Paediatric bone tumours and tumour-like lesions of the clavicle majority of clavicular tumours are malignant Ewing sarcoma (most common) o...
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Paediatric curriculum

The paediatric curriculum is one of our curriculum articles and aims to be a collection of articles that represent the core paediatric knowledge. Definition Topics pertaining to paediatric radiology, including paediatric neuroradiology and fetal radiology, although there will be some cross cov...
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Paediatric cystic renal diseases

The paediatric cystic renal diseases comprises a group of conditions that are all either autosomal recessive or non-hereditary: autosomal recessive polycystic kidney disease (ARPKD): hyperechoic and enlarged kidney multicystic dysplastic kidney (MCDK): absence of functional parenchyma, urete...
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Paediatric elbow radiograph (an approach)

Paediatric elbow radiographs are commonly encountered in the emergency department and, when approached in a systematic fashion, are not as difficult to interpret as most people think! Systematic review Ossification Check that the ossification centres are present and in the correct position. T...
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Paediatric kidney size

The paediatric kidneys follow a growth curve. The measurements below are of the longest maximal dimension. Measurements in parentheses are one standard deviation. 0 months 1:  female: 4.15 cm (0.35); male: 4.22 cm (0.32) 2 months: 5.28 cm (0.66) 6 months: 6.15 cm (0.67) 10 months: 6.23 cm (0...
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Paediatric mediastinal masses

Paediatric mediastinal masses are the most common chest masses in children, with the anterior mediastinum being the most common site 1. As in adults, mediastinal masses are classified depending on anatomical sites: anterior mediastinal masses middle mediastinal masses posterior mediastinal m...
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Paediatric midface anomalies (classification)

This classification system based on the embryology and anatomy of the nasal cavity, nasofrontal region, and nasolacrimal apparatus as well as anomalies associated with craniofacial syndromes.2 Nasal cavity choanal atresia and stenosis pyriform aperture stenosis Nasofrontal region  conge...
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Paediatric posterior fossa tumours (mnemonic)

Tumours of the posterior fossa in children can be remembered using the mnemonic: BEAM Mnemonic The mnemonic is not in order of prevalence; pilocytic astrocytomas are most common. B: brainstem glioma E: ependymoma A: astrocytoma (pilocytic) (85%) M: medulloblastoma
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Paediatric renal tumours and masses

Paediatric renal tumours and masses are another group of diseases (just like cystic renal diseases in both the adult and child) that are bewildering in their number, nomenclature and overlapping findings. Commoner lesions Wilms tumour: common in older children 1-8 years old mesoblastic nephro...
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Paediatric skeletal metasases (differential)

There is a wide range of primary malignancies that results in paediatric skeletal metastases 1: neuroblastoma leukaemia: although not truly metastases lymphoma clear cell sarcoma: Wilms’ variant rhabdomyosarcoma retinoblastoma Ewing’s sarcoma: lung metastases much more common osteosarcom...
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Paediatric urinary tract infection

Paediatric urinary tract infections are common and are a source of significant imaging in young children. Epidemiology Paediatric urinary tract infections affect up to 2.8% of all children every year, with approximately 2% of boys and 8% or more of girls developing a urinary tract infection at...
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Paediatric urinary tract infection (NICE guideline)

The British National Institute for Health and Care Excellence (NICE) published the “Urinary tract infection in under 16s: diagnosis and management” in 2007 as a guideline for paediatric urinary tract infection (UTI) management, including imaging, prophylaxis and follow-up 1.  This article inten...
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Pallister-Hall syndrome

Pallister-Hall syndrome is characterised by: hypothalamic hamartomas anal atresia renal anomalies, e.g horseshoe kidney limb malformations polydactyly cutaneous syndactyly bifid epiglottis
Article

Pancreatoblastoma

Pancreatoblastomas are rare paediatric tumours of the pancreas. However, they are the most common pancreatic neoplasm of childhood and are often associated with a raised alpha-fetoprotein. Epidemiology There is slight male predilection. Usually occurs in the first decade of life with a mean ag...
Article

Panner disease

Panner disease is an osteochondrosis of the capitellum. It should be distinguished from osteochondritis dissecans of the elbow which also affects the capitellum.  Epidemiology Panner disease is typically seen in children (5-10 years of age), although it is also seen in throwers due to repeated...
Article

Parachute mitral valve

A parachute mitral valve is a valvular congenital abnormality usually identified in infants or young children though is can present later in adulthood. Pathology Parachute mitral valves occur when all the chordae tendineae are attached to a single papillary muscle origin. Unlike the normal sit...
Article

Parapagus

Parapagus twins are conjoined twins that lie side-by-side with ventrolateral fusion.  This type of conjoined twins usually shares the umbilicus, abdomen, and pelvis. The conjoined pelvis may have a single symphysis pubis and one or two sacra.  The lower gastrointestinal tract (single colon and...
Article

Patau syndrome

Patau syndrome (also known as trisomy 13) is considered the 3rd commonest autosomal trisomy. This along with Down syndrome (T21) and Edward syndrome (T18) are the only three trisomies to be compatible with extrauterine life. However, few infants live more than a few days.  Epidemiology The es...
Article

Patellar sleeve fractures

Patellar sleeve fractures represent chondral or osteochondral avulsion injury at the inferior pole of the patella. Epidemiology Patellar sleeve fractures occur in the paediatric population, typically between 8 and 12 years of age. Clinical presentation Unlike Sinding-Larsen-Johannson disease...
Article

Patent ductus arteriosus

Patent ductus arteriosus or arteriosum (PDA) is a congenital cardiac anomaly where there is persistent patency of the ductus arteriosus, a normal connection of the fetal circulation between the aorta and the pulmonary arterial system that develops from the 6th aortic arch. Epidemiology PDAs oc...
Article

Patent urachus

A patent urachus is one of the spectrum of congenital urachal anomalies. It has occasionally been termed "urachal fistula". Clinical presentation A patent urachus is often diagnosed in neonates when urine is noted leaking from the umbilicus. The umbilicus may also have an abnormal appearance o...
Article

Patterns of neonatal hypoxic–ischaemic brain injury

Neonatal hypoxic ischaemic brain injuries can manifest in different patterns of involvement depending on the severity and timing of the insult. When considering the perinatal maturation process of the brain and the severity of an insult, it is possible to understand the various manifestations. ...
Article

PECARN traumatic brain injury algorithm

The PECARN (Paediatric Emergency Care Applied Research Network) traumatic brain injury algorithm is a clinical decision rule that aims to identify children at very low risk of clinically important traumatic brain injury (ci-TBI) 1. This validated paediatric algorithm predicts likelihood of the a...
Article

Pectus carinatum

Pectus carinatum (otherwise known as a pigeon chest) refers to a chest wall deformity in which the sternum protrudes anteriorly. It is less common than pectus excavatum. Clinical presentation Patients may present with dyspnoea and exercise intolerance. Pathology Associations scoliosis (comm...
Article

Pectus excavatum

Pectus excavatum (or funnel chest) is a congenital chest wall deformity characterised by concave depression of the sternum, resulting in cosmetic and radiographic alterations. Epidemiology It is the most common chest wall deformity, accounting for approximately 90%, and occurs in up to 1 in 30...
Article

Pelvi-ureteric junction obstruction

Pelvi-ureteric junction (PUJ) obstruction/stenosis, also known as ureteropelvic junction (UPJ) obstruction/stenosis, can be one of the causes of an obstructive uropathy. It can be congenital or acquired with a congenital PUJ obstruction being one of the commonest causes of antenatal hydronephros...
Article

Pelvic osteotomy

Pelvic osteotomy relates to an orthopaedic treatment for developmental acetabular dysplasia of the hip. The main purpose of pelvic osteotomy is the prevention of early degenerative changes by stabilisation of the hip and redistribution of joint loading. It is obtained by surgical re-shaping/ re...
Article

PELVIS syndrome

PELVIS or LUMBAR syndrome is the combination of pelvic haemangiomas with other extracutaneous abnormalities. The syndrome may be incomplete.   Pathology PELVIS perineal haemangiomas external genital malformations lipomyelomeningocele vesicorenal anomalies imperforate anus skin tag LUMBA...
Article

Pentalogy of Cantrell

The pentalogy of Cantrell is an extremely rare phenomenon with an incidence estimated at around 6 per million live births 3.  It encompasses the following 5 main features 1. omphalocoele ectopia cordis (abnormal location of heart) diaphragmatic defect pericardial defect or sternal cleft ca...
Article

Pentalogy of Fallot

The pentalogy of Fallot is a variant of the more common tetralogy of Fallot, comprising the classical four features with the addition of an atrial septal defect or patent ductus arteriosus The five features therefore are: ventricular septal defect (VSD)  right ventricular outlfow tract narro...
Article

Pepper syndrome

Pepper syndrome is of interest only (the term is not readily used in day-to-day practice), and refers to primary adrenal neuroblastoma with extensive liver metastases 1. In essence, it refers to stage 4S neuroblastoma (see staging of neuroblastoma). 

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