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23 results found

2005 WHO histological classification of odontogenic tumours

The 2005 WHO histological classification of odontogenic tumours lays out a classification system for neoplasms and other tumours related to the odontogenic apparatus. At the time of writing (2016), it is still the most widely used classification system although a new revision is due to come up i...

2008 WHO classification of tumours of haematopoietic and lymphoid tissues

The 2008 WHO classification of tumours of haematopoietic and lymphoid tissues is at the time of writing (mid 2016) the most widely used classification system.   Classification Hodgkin lymphoma nodular lymphocyte predominance classical Hodgkin lymphoma nodular sclerosing mixed cellularity ...

2014 WHO classification of endometrial stromal tumours

Endometrial stromal tumours (EST) constitute <2% of all uterine tumours and <10% of uterine mesenchymal neoplasms 1.  Over the past four decades, EST classification has gone through various modifications, starting from the earliest study by Norris and Taylor 2. This was primarily due to the rar...

Bethesda criteria of hereditary non-polyposis colorectal cancer

The Bethesda criteria are an alternative to the Amsterdam criteria for the clinical diagnosis of hereditary non-polyposis colorectal cancer (HNPCC).  Diagnosis of HNPCC is made if any of the following criteria are fulfilled: Amsterdam criteria are met 2 or more HNPCC related malignancies  pa...


A BIRADS IV lesion under the breast imaging reporting and data system refers to a suspicious abnormality. BIRADS IV lesions may not have the characteristic morphology of breast cancer but have a definite probability of being malignant. A biopsy is recommended for these lesions. If possible, the ...

Breast imaging-reporting and data system (BI-RADS)

BI-RADS classification is proposed by the American College of Radiology (ACR), last updated in November 2015, and is a widely used classification system at the time of writing this article (July 2016). The BI-RADS acronym stands for Breast Imaging-Reporting and Data System which is a widely acc...

Choi response criteria

Use only the size of the tumor during evaluation of response to chemotherapy has some pitfalls and limitations, especially when the estimated response for specific tumors such as gastrointestinal stromal tumour (GIST). The Choi response criteria for GIST proposed that tumour attenuation could p...

Fukuoka consensus guidelines

The Tanaka criteria, also referred to as the Fukuoka consensus guidelines, is a classification system for intraductal papillary mucinous neoplasms (IPMNs) and mucinous cystic neoplasms (MCNs).  The prior international consensus guidelines (2006) were referred to as the Sendai criteria, which la...

Gynaecologic imaging reporting and data system (GI-RADS)

The Gynecologic Imaging Reporting and Data System (GI-RADS) is a reporting system that was created for reporting the findings in adnexal masses based on transvaginal ultrasonography. Classification Findings are classified into five categories 1: GI-RADS 1 normal ovaries identified and no adn...

Ishikawa classification of venous involvement by pancreatic ductal adenocarcinoma

Ishikawa classification system describes the degree of involvement of adjacent portal vein and SMV by pancreatic ductal adenocarcinoma based on calibre of the vein: type I: normal  type II: smooth shift/displacement with normal calibre   type III: unilateral narrowing  type IV: bilateral nar...

Krenning score of neuroendocrine tumour uptake

The Krenning score is a proposed semi-quantitative method of assessing the degree of tracer uptake on octreotide scintigraphy. Parameters Initially designed for assessment of 111In-DTPA on planar imaging, the Krenning score is applicable to SPECT or SPECT/CT using various radiopharmaceuticals....

Lugano classification: response evaluation criteria for CT and PET/CT

The Lugano classification recommends two methods of visualization for standing lymphoma: Computer tomography (CT) Positron emission tomography–computed tomography (PET/CT) Response Assessment on CT   CT uses for the standing of all types of lymphoma (if CT is performed for tumor size measure...

Myeloproliferative disorder

Myeloproliferative disorders (MPDs) are a diverse group of conditions that are characterised by the overproduction of red cells, white cells and/or platelets in bone marrow. There are numerous conditions considered in this group but the most common are:  myelofibrosis polycythaemia vera essen...

Prostate Imaging Reporting and Data System

PI-RADS (Prostate Imaging Reporting and Data System) refers to a structured reporting scheme for evaluating the prostate for prostate cancer. It is designed to be used in a pre-therapy patient. The original PI-RADS score was annotated, revised and published as the second version, PI-RADS v2 6, ...


RASopathies are a class of developmental disorders caused by germline mutations in genes that encode for components or regulators of the Ras/mitogen activated protein kinase (MAPK) pathway. Epidemiology As a group, RASopathies represent one of the most common malformation syndromes, with an in...

RECIST 1.1: comparison with RECIST 1.0

Response Evaluation Criteria In Solid Tumours (RECIST) was updated to version 1.1 in 2009. For both RECIST 1.0 and 1.1, the requirement for measurable disease at baseline depends on the endpoints of the clinical trial. The fundamental concept common to both versions of RECIST is that measurabl...

Spinal instability neoplastic score (SINS)

The spinal instability neoplastic score (SINS) helps to assess tumour related instability of the vertebral column. It has been shown to useful in guiding the mobilisation or operative management of patients with neoplastic spinal disease. Studies have reported good inter-observer agreement amon...

Spinal metastases

Spinal metastases is a vague term which can be variably taken to refer to metastatic disease to any of the following: vertebral metastases (94%) may have epidural extension intradural extramedullary metastases (5%) intramedually metastases (1%) Each of these are discussed separately. Below ...

Squamous cell carcinoma (head and neck)

Squamous cell carcinomas (SCC) of the head and neck are common, being the sixth most common cancer. They can have a cutaneous or mucosal origin. As such there is a wide array of clinical and radiographic manifestations, and are separated into: squamous cell carcinoma of the skin of the head and...

Tumours of the male urethra

Tumours of the male urethra are uncommon. They can be categorised both on the grounds of histology and location. Histology squamous cell carcinoma of the urethra: 80% urothelial/transitional cell carcinoma of the urethra: 15% (predominantly posterior urethra) adenocarcinoma of the urethra: 5...

WHO classification of anal margin tumours

The WHO classification of anal margin tumours or perianal skin tumours is: intraepithelial tumours Bowen disease (precursor of squamous cell carcinoma) Paget's disease (precursor of adenocarcinoma) invasive tumours squamous cell carcinoma adenocarcinoma basal cell carcinoma  verrucous ca...

WHO classification scheme for thymic epithelial tumours

The WHO classification scheme for thymic epithelial tumours is one of many classifications systems for thymoma and related tumours, and classifies them according to histology: type a medullary thymoma spindle cell thymoma type ab: mixed thymoma type b1: lymphocyte rich predominantly cortic...

WHO histological classification of tumours of the uterine cervix

The WHO histological classification is a detailed classification of tumours of the uterine cervix. epithelial tumours squamous tumours and precursors squamous cell carcinoma, not otherwise specified - 8070/3 keratinizing - 8071/3 non-keratinizing - 8072/3 basaloid - 8083/3 verrucous - 805...

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