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Serum CA-125 is well recognised as an ovarian cancer-associated marker and is an antigen determinant on a high-molecular-weight glycoprotein. The normal range of CA-125 is 0-35 U/mL. Serum CA-125 levels can also be used to monitor the response to treatment as well as a prognostic indicator sinc...

CA 19-9 elevation

CA 19-9 (carbohydrate antigen 19-9 or cancer antigen) is a serum antigen (monosialoganglioside) that has increased diagnostic use in the management of several malignancies, mainly of hepatopancreaticobiliary origin. It is non-specific, however, and can rise in both malignant and non-malignant co...

Carcinoembryonic antigen

Serum carcinoembryonic antigen (CEA) is a cell-adhesive glycoprotein that was discovered in colorectal cancer in 1965, and is hence one of the oldest and most used tumour markers. Its name derives from its normal expression in fetoembryonic liver, gut and pancreas tissue. Normal range of CEA is...

Hepatoblastoma histological classification

Although hepatoblastomas can be histologically classified into a variety of sub types, it is important to remember that with the possible exception of small cell undifferentiated sub type, prognosis is independent of histology when adjusted for stage gender and age 1. major categories epitheli...

Hypertriglyceridaemia-induced pancreatitis

Hypertriglyceridaemia-induced pancreatitis is an uncommon form of acute pancreatitis caused by high levels of circulating triglycerides in the blood. Epidemiology Hypertriglyceridaemia-induced pancreatitis accounts for around 1-4% of cases of acute pancreatitis and is the third most common cau...

Liquefactive necrosis

Liquefactive necrosis is a form of necrosis where there is transformation of the tissue into a liquid viscous mass. Pathology In liquefactive necrosis, the affected cell is completely digested by hydrolytic enzymes leading to a soft, circumscribed lesion which can consist of fluid with remains...


A pseudocyst is an abnormal fluid-filled cavity which is not lined by epithelium.  It is this fact that distinguishes it pathologically from a cyst, which is lined by epithelium. Examples of pseudocysts are: pancreatic pseudocyst pulmonary pseudocyst pseudocysts of the germinal matrix

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