Cronkhite-Canada Syndrome is a rare gastro-intestinal pathology with an uncertain etiology. Approximately 500 cases have been reported in the literature1. It has been described as a protein-losing enteropathy, and presents with sequalae of malnutrition, diarrhea, alopecia, nail dystrophy and skin hyperpigmentation.
Discussion in the literature has mostly focused on clinical and histolopathological sequalae, with radiological characterization lacking. Those studies that have described these focus primarily on fluoroscopic manifestations. Common findings include involvement of the stomach, duodenum and large bowel, with variable involvement of the jejunum and ileum1,2. The esophagus appears to be spared.
On follow-through studies, described findings include peripheral "whiskering" either due to polypoid carpeting of the mucosa, or due to area gastrica. Other findings include diffuse nodularity, rugal and haustral thickening and sessile and polypoid filling defects2.
Findings on CT mirror those on fluoroscopy, in this case demonstrating diffuse polyps throughout the stomach, duodenum and large bowel. The duodenum was prominently affected in this case, which may be a combination of polyps and edema.
This case was donated to radiopaedia by the Dr. G. M. Moro Film Library